Jamal Karim, Challacombe Ben, Elhage Oussama, Popert Rick, Kirby Roger, Dasgupta Prokar
Department of Urology, Guy's Hospital and King's College London School of Medicine, London, United Kingdom.
Urology. 2008 Dec;72(6):1356-8. doi: 10.1016/j.urology.2008.04.007. Epub 2008 Jun 4.
We describe the first case of salvage robotic-assisted radical prostatectomy for local recurrence after external beam radiotherapy. A 50-year-old man initially underwent combined external beam radiotherapy and hormonal treatment for Stage T2a prostate adenocarcinoma. The prostate-specific antigen level was 10.5 ng/mL, and the Gleason score was 3+3. Two years later, he developed biopsy-proven recurrent disease. He underwent salvage robotic-assisted radical prostatectomy. The patient was discharged on day 1 postoperatively. The histologic analysis revealed an organ-confined tumor. His prostate-specific antigen at 3 months was <0.03 ng/mL, and he was continent. Salvage robotic-assisted radical prostatectomy is a safe and technically feasible salvage treatment for prostate cancer for which primary radiotherapy has failed.
我们描述了首例针对外照射放疗后局部复发进行挽救性机器人辅助根治性前列腺切除术的病例。一名50岁男性最初因T2a期前列腺腺癌接受了外照射放疗和激素治疗联合方案。前列腺特异性抗原水平为10.5 ng/mL，Gleason评分3+3。两年后，他经活检证实出现复发性疾病。他接受了挽救性机器人辅助根治性前列腺切除术。患者术后第1天出院。组织学分析显示肿瘤局限于器官内。他术后3个月时前列腺特异性抗原<0.03 ng/mL，且控尿良好。挽救性机器人辅助根治性前列腺切除术对于原发性放疗失败的前列腺癌而言是一种安全且技术上可行的挽救性治疗方法。
