Terekhova N V, Khazanova V V, Zemskaia E A, Bykova I A, Filonenko O F, Kosorukova N Ia, Rabinovich I M
Stomatologiia (Mosk). 1991 Mar-Apr(2):35-7.
The authors sum up the experience gained in tactivin therapy of patients with recurrent aphthous stomatitis and analyze the effects of this drug on the patients' cellular and humoral immunity. Thirty patients with various forms of the condition were subcutaneously injected tactivin in a dose of 40 micrograms for 10 days. Biochemical parameters were virtually unchanged after therapy, whereas the immunity parameters evidenced essential shifts in humoral and cellular immunity. Clinical and laboratory data indicate a sufficiently high immunocorrective effect of tactivin in therapy of patients with recurrent aphthous stomatitis.
作者总结了在复发性阿弗他口炎患者中使用他克莫司治疗所获得的经验，并分析了该药物对患者细胞免疫和体液免疫的影响。30例患有各种形式该病的患者皮下注射40微克剂量的他克莫司，持续10天。治疗后生化指标基本未变，而免疫指标显示体液免疫和细胞免疫有显著变化。临床和实验室数据表明，他克莫司在复发性阿弗他口炎患者治疗中具有足够高的免疫纠正作用。
