Castaigne P, Cathala H P, Brunet P, Hauw J J, Sicard J P
J Neurol Sci. 1976 Nov;30(1):65-82. doi: 10.1016/0022-510x(76)90256-2.
The authors report 5 personal cases (3 in the same family) of patients suffering from recurrent peripheral nerve palsies usually induced by pressure and review the relevant literature. There is evidence in such cases of a mild, chronic, diffuse, subclinical neuropathy which can be recognized by electrophysiological examination. Examination of peripheral nerve biopsy material in such cases shows evidence of both axonal and Schwann cell abnormalities with evidence of neurogenic atrophy of skeletal muscles. This chronic subclinical neuropathy which is often familial can be distinguished from other chronic primary neuropathies with or without myelin sheath proliferation and hypertrophy.
作者报告了5例(其中3例来自同一家族)常因受压而反复发作周围神经麻痹的患者,并回顾了相关文献。在这些病例中,有证据表明存在一种轻度、慢性、弥漫性、亚临床神经病变,可通过电生理检查识别。对这些病例的周围神经活检材料进行检查,显示出轴突和施万细胞均有异常,并有骨骼肌神经源性萎缩的证据。这种常为家族性的慢性亚临床神经病变可与其他伴有或不伴有髓鞘增生和肥大的慢性原发性神经病变相鉴别。