Høgh Annette Langager, Sandermann Jes, Lindholt Jes S
Regionshospitalet Viborg, Karkirurgisk Afdeling, Viborg.
Ugeskr Laeger. 2008 Jun 2;170(23):2003-5.
Our expectation is that the numbers of diagnosed small abdominal aortic aneurysms (AAA) will increase in the future. Slowing down the progression of AAAs is of great interest as this could prevent cost-intensive and potential lethal operations. Recent studies indicate that modern medical treatment such as prevention for cardiovascular disease has a spin-off benefit by suppressing the expansion rate of AAAs. According to these studies ACE inhibitors, statins and nonsteroidal anti-inflammatory drugs may have effect, macrolides may have some effect while beta-blockers and calcium-channel blockers have no effect.
我们预计,未来诊断出的小型腹主动脉瘤(AAA)数量将会增加。减缓腹主动脉瘤的进展备受关注,因为这可以避免成本高昂且可能致命的手术。最近的研究表明,诸如心血管疾病预防等现代医学治疗手段通过抑制腹主动脉瘤的扩张率而具有附带益处。根据这些研究,血管紧张素转换酶抑制剂、他汀类药物和非甾体抗炎药可能有效果,大环内酯类药物可能有一定效果,而β受体阻滞剂和钙通道阻滞剂则没有效果。