Brettar Ingrid, Höfle Manfred G
Department of Vaccinology and Applied Microbiology, Helmholtz Centre of Infection Research (HZI), Inhoffenstr. 7, D-38124 Braunschweig, Germany.
Curr Opin Biotechnol. 2008 Jun;19(3):274-80. doi: 10.1016/j.copbio.2008.04.004. Epub 2008 Jun 3.
Human bacterial pathogens are considered as an increasing threat to drinking water supplies worldwide because of the growing demand of high-quality drinking water and the decreasing quality and quantity of available raw water. Moreover, a negative impact of climate change on freshwater resources is expected. Recent advances in molecular detection technologies for bacterial pathogens in drinking water bear the promise in improving the safety of drinking water supplies by precise detection and identification of the pathogens. More importantly, the array of molecular approaches allows understanding details of infection routes of waterborne diseases, the effects of changes in drinking water treatment, and management of freshwater resources.
由于对优质饮用水的需求不断增加，以及可用原水的质量和数量不断下降，人类细菌病原体被认为对全球饮用水供应构成越来越大的威胁。此外，气候变化预计会对淡水资源产生负面影响。饮用水中细菌病原体分子检测技术的最新进展有望通过精确检测和识别病原体来提高饮用水供应的安全性。更重要的是，一系列分子方法有助于了解水传播疾病的感染途径细节、饮用水处理变化的影响以及淡水资源的管理。
