Löfmark Ulrika, Hammarström Anne
Family Medicine, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Neuroepidemiology. 2008;31(1):21-7. doi: 10.1159/000136647. Epub 2008 Jun 6.
There is strong evidence for the existence of a socioeconomic gradient in stroke incidence and mortality, but there seem to be contradictory findings concerning an association between socioeconomic status and case fatality after stroke. Moreover, there is still a lack of studies that include men and women as well as people over 75 years. Our aim was to investigate whether there were education-related differences in 28-day case fatality after stroke in different age groups.
All patients who were diagnosed with a cerebral infarction at the Umeå University Hospital during a 2-year period were included in this study.
In total, 610 stroke patients (331 men, 279 women) aged 20-85 were hospitalized, of whom 77% were first-ever strokes. Overall, there were few education-related differences between the patients in different age groups (20-74 and 75-85 years). The 28-day case fatality after stroke was shown to be associated with a low educational level in patients above 75 years, also after controlling for sex, risk factors and acute stroke care measures.
In this population-based study on patients with cerebral infarction, we found an education-related difference in 28-day case fatality in patients aged 75-85 years. The socioeconomic gradient persisted when we adjusted for risk factors and acute care variables. There is a need for more community-based stroke studies including all ages, with good case ascertainment.
有充分证据表明中风发病率和死亡率存在社会经济梯度,但关于社会经济地位与中风后病死率之间的关联似乎存在相互矛盾的研究结果。此外,仍然缺乏涵盖男性和女性以及75岁以上人群的研究。我们的目的是调查不同年龄组中风后28天病死率是否存在与教育程度相关的差异。
本研究纳入了在乌梅奥大学医院两年期间被诊断为脑梗死的所有患者。
共有610例年龄在20 - 85岁的中风患者(331名男性,279名女性)住院,其中77%为首次中风。总体而言,不同年龄组(20 - 74岁和75 - 85岁)患者之间与教育程度相关的差异较少。在控制了性别、危险因素和急性中风护理措施后,75岁以上患者中风后28天病死率与低教育水平相关。
在这项基于人群的脑梗死患者研究中,我们发现75 - 85岁患者中风后28天病死率存在与教育程度相关的差异。在调整危险因素和急性护理变量后,社会经济梯度依然存在。需要开展更多涵盖所有年龄段、病例确定良好的基于社区的中风研究。