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专科药物成功的驱动因素是什么?

What drives success for specialty pharmaceuticals?

作者信息

Gudiksen Mark, Fleming Edd, Furstenthal Laura, Ma Philip

机构信息

McKinsey & Company, 3075A Hansen Way, Palo Alto, California 94304, USA.

出版信息

Nat Rev Drug Discov. 2008 Jul;7(7):563-7. doi: 10.1038/nrd2594. Epub 2008 Jun 6.

DOI:10.1038/nrd2594
PMID:18535582
Abstract

Specialty pharmaceuticals have become increasingly important in the global pharmaceutical landscape. Numerous large pharmaceutical companies are moving towards developing therapies for specialty markets, which are attractive owing to factors including the established commercial track record and lower commercial infrastructure costs. In this article, we analyse the key drivers of commercial success and failure for specialty pharmaceuticals.

摘要

专科药物在全球制药格局中变得越来越重要。许多大型制药公司正朝着开发针对专科市场的疗法迈进,这些市场因既有商业记录和较低的商业基础设施成本等因素而颇具吸引力。在本文中,我们分析了专科药物商业成功与失败的关键驱动因素。

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What drives success for specialty pharmaceuticals?专科药物成功的驱动因素是什么?
Nat Rev Drug Discov. 2008 Jul;7(7):563-7. doi: 10.1038/nrd2594. Epub 2008 Jun 6.
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Market watch: Specialty pharmaceuticals to provide majority of sales by 2012.市场观察:到2012年,专科药品将占销售额的大部分。
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Application of Pharmacokinetics and Pharmacodynamics in Product Life Cycle Management. A Case Study with a Carbidopa-Levodopa Extended-Release Formulation.药代动力学和药效学在产品生命周期管理中的应用。以卡比多巴-左旋多巴缓释制剂为例的案例研究。
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APT drug R&D: the right active ingredient in the right presentation for the right therapeutic use.
APT药物研发:正确的活性成分,以正确的剂型用于正确的治疗用途。
Nat Rev Drug Discov. 2009 Nov;8(11):849-53. doi: 10.1038/nrd2981. Epub 2009 Aug 28.