Badami Krishna G, Taylor Kate
New Zealand Blood Service, 87 Riccarton Rd., Christchurch, New Zealand.
N Z Med J. 2008 May 23;121(1274):50-60.
To assess the iron status of New Zealand blood donors using the serum ferritin (ferritin) assay and the impact of gender, age, and donation history on iron status.
Ferritin levels were measured in 5006 subjects attending two New Zealand Blood Service (NZBS) blood donor sites between October and December 2006. The influence of three major determinants of iron status (gender, age, and blood donation history) in the previous 12 months was assessed.
Ferritin levels tended to be lower in younger people, females, and those with more intensive blood donation history. Levels lower than 12 mcg/L were found in 14.1% of subjects overall, 19.9% of females, 19.0 % of those aged under 20 years, and 25.1% of those who had donated 3-4 whole blood units during the previous 12 months had ferritin levels lower than 12 mcg/L. Risks were additive and total risk correlated inversely with ferritin levels.
Iron deficiency is a significant problem in New Zealand blood donors. Prevention or treatment, as appropriate, would help both donors and the long-term supply of blood. A stratified approach to testing, prevention and treatment taking into account risk factors, ferritin and Hb levels is likely to be the most effective strategy.
采用血清铁蛋白检测评估新西兰献血者的铁状态，以及性别、年龄和献血史对铁状态的影响。
于2006年10月至12月间，对前往两个新西兰血液服务（NZBS）献血点的5006名受试者测定铁蛋白水平。评估了过去12个月中铁状态的三个主要决定因素（性别、年龄和献血史）的影响。
年轻人、女性以及献血史更频繁者的铁蛋白水平往往较低。总体上14.1%的受试者铁蛋白水平低于12微克/升，女性中有19.9%，20岁以下者中有19.0%，以及在过去12个月内捐献了3 - 4个全血单位的人中，有25.1%的铁蛋白水平低于12微克/升。风险具有叠加性，总风险与铁蛋白水平呈负相关。
缺铁在新西兰献血者中是一个重大问题。适当的预防或治疗将对献血者和长期血液供应都有帮助。考虑到风险因素、铁蛋白和血红蛋白水平，采用分层方法进行检测、预防和治疗可能是最有效的策略。
