15月龄健康儿童中同时接种甲型肝炎灭活疫苗和肺炎球菌结合疫苗的免疫原性及安全性
Immunogenicity and safety of an inactivated hepatitis a vaccine administered concomitantly with a pneumococcal conjugate vaccine in healthy children 15 months of age.
作者信息
Trofa Andrew F, Levin Michael, Marchant Colin D, Hedrick James, Blatter Mark M
机构信息
Department of Clinical Research, Development, and Medical Affairs, Vaccines for Viral Diseases, GlaxoSmithKline, King of Prussia, PA 19406, USA.
出版信息
Pediatr Infect Dis J. 2008 Jul;27(7):658-60. doi: 10.1097/INF.0b013e31816907bd.
The immunogenicity and safety of hepatitis A vaccine and pneumococcal conjugate vaccine, administered separately or concomitantly in children 15 months of age, were evaluated. After completed vaccinations, antihepatitis A and antipneumococcal geometric mean concentrations were similar across groups. Both vaccines were well-tolerated when given concomitantly during the second year of life.
对15个月大儿童单独或同时接种甲型肝炎疫苗和肺炎球菌结合疫苗的免疫原性和安全性进行了评估。完成疫苗接种后，各组的抗甲型肝炎和抗肺炎球菌几何平均浓度相似。在生命的第二年同时接种这两种疫苗时，耐受性均良好。
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