White James D, Demnitz F W J, Xu Qing, Martin William H C
Department of Chemistry, Oregon State University, Corvallis, Oregon 97331, USA.
Org Lett. 2008 Jul 3;10(13):2833-6. doi: 10.1021/ol8009732. Epub 2008 Jun 7.
Condensation of an orsellinate anion with a 2-cyclohexenone (Staunton-Weinreb annulation) afforded a linear tetracycle which was converted to a protected derivative of 12a-epipillaromycinone. Methodology for introducing a 12a-hydroxyl substituent into the tetracycle with correct (R) configuration is described.
苔色酸阴离子与2-环己烯酮缩合（斯陶顿-魏因雷布环化反应）得到一个线性四环化合物，该化合物被转化为12a-表柱霉素酮的一个保护衍生物。描述了将具有正确（R）构型的12a-羟基取代基引入四环化合物的方法。
