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[促性腺激素释放激素拮抗剂在子宫内授精的卵巢刺激中的应用:有意义吗?]

[The use of GnRH antagonists in ovarian stimulation for intrauterine inseminations: is there any interest?].

作者信息

Pasquier M, Maitrot L, Leperlier F, Dehghani C, Snaifer E, Durnerin I-C, Hugues J-N

机构信息

Service de médecine de la reproduction, université Paris-XIII, CHU Jean-Verdier, avenue du 14-Juillet, 93140 Bondy, France.

出版信息

Gynecol Obstet Fertil. 2008 Jun;36(6):644-9. doi: 10.1016/j.gyobfe.2008.03.014. Epub 2008 Jun 6.

DOI:10.1016/j.gyobfe.2008.03.014
PMID:18539072
Abstract

The use of the GnRH antagonists during ovarian stimulation for intrauterine insemination is relatively recent. The primary aim was to improve the timing of the inseminations on working days. However, according to published data, the consequences on pregnancy rate remain uncertain. Moreover, the impact of this strategy on stimulation's parameters, specifically on the size of the follicle cohort, should be better assessed.

摘要

在卵巢刺激用于宫内人工授精过程中使用促性腺激素释放激素(GnRH)拮抗剂是相对较新的做法。主要目的是改善工作日进行人工授精的时间安排。然而,根据已发表的数据,对妊娠率的影响仍不确定。此外,这种策略对刺激参数的影响,特别是对卵泡群大小的影响,应得到更好的评估。

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