Cottrell Jocelyn M, Scholten Paul, Wanich Tony, Warren Russell F, Wright Timothy M, Maher Suzanne A
Department of Biomechanics, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.
J Biomech. 2008 Jul 19;41(10):2324-9. doi: 10.1016/j.jbiomech.2008.04.024. Epub 2008 Jun 9.
Studies of the load transfer role of the meniscus have been limited to static experimental and analytical approaches. The objective of this study was to develop an experimental technique to allow the contact pressures on the tibial plateau of cadaveric knees to be measured under dynamic physiological loads. Accordingly, we adapted a load-controlled knee joint simulator to accept a cadaveric sheep knee, programmed the simulator with sheep gait kinematics data, and utilized a pressure sensor array to measure the contact pressure distribution on the lateral tibial plateau during gait. The technique was applied to six sheep knees that were tested intact and after meniscectomy. Meniscectomy resulted in a 267% increase in average contact pressure, a 117% increase in peak contact pressure, and an 80% decrease in contact area, all measured at the point of maximum peak contact stress in the gait cycle. It is envisaged that the experimental model herein developed will allow for the screening of candidate materials prior to more expensive and time-consuming animal models.
对半月板负荷传递作用的研究一直局限于静态实验和分析方法。本研究的目的是开发一种实验技术,以便在动态生理负荷下测量尸体膝关节胫骨平台上的接触压力。因此,我们对一个负荷控制的膝关节模拟器进行了改装,使其能够容纳一具尸体羊膝关节,用羊的步态运动学数据对模拟器进行编程,并利用压力传感器阵列测量步态期间外侧胫骨平台上的接触压力分布。该技术应用于六个完整的羊膝关节以及半月板切除术后的羊膝关节。半月板切除术导致平均接触压力增加267%,峰值接触压力增加117%,接触面积减少80%,所有这些都是在步态周期中最大峰值接触应力点处测量的。预计本文开发的实验模型将允许在更昂贵且耗时的动物模型之前筛选候选材料。