Oshorov A V, Savin I A, Goriachev A S, Popugaev K A, Potapov A A, Gavrilov A G
Anesteziol Reanimatol. 2008 Mar-Apr(2):61-4.
The paper presents the first experience in monitoring the pressure reactivity index (Prx) of cerebral vascular autoregulation in a group of patients with severe brain injury. This autoregulation index along with the monitored parameters of intracranial pressure (ICP) and cerebral perfusion pressure (CPP) allows the outcome to be predicted in brain injury: the outcome is poor at a Prx of > 0.2. The continuous estimation of the autoregulation index makes it possible to determine the optimum CPP value for each patient and to timely diagnose decompensation of cerebral vascular autoregulation, which is of importance in selecting treatment policy.
本文介绍了对一组重型脑损伤患者脑血管自动调节压力反应性指数（Prx）进行监测的首次经验。该自动调节指数与颅内压（ICP）和脑灌注压（CPP）的监测参数一起，能够预测脑损伤的预后：当Prx>0.2时预后较差。对自动调节指数的持续评估能够确定每位患者的最佳CPP值，并及时诊断脑血管自动调节功能失代偿，这对于选择治疗策略具有重要意义。
