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认证乳腺中心乳房切除术的预测因素——外科医生是一个独立的风险因素。

Predictors of mastectomy in a certified breast center - the surgeon is an independent risk factor.

作者信息

Reitsamer Roland, Menzel Christian, Glueck Sylvia, Hitzl Wolfgang, Peintinger Florentia

机构信息

Department of Senology, Breast Center Salzburg, University Hospital Salzburg, Paracelsus Private Medical School Salzburg, Salzburg, Austria.

出版信息

Breast J. 2008 Jul-Aug;14(4):324-9. doi: 10.1111/j.1524-4741.2008.00592.x.

Abstract

The current study examined predictors of mastectomy in a certified breast center with the main impact on the factor surgeon. A total of 663 patients were analyzed for their mastectomy rates. Included were patients with T1 and T2 tumors, who had their surgery performed by one of three specialized breast surgeons with a workload of at least 50 new breast cancer cases per year. On multivariate analysis central tumor localization, positive lymph node status, nonunifocality, large tumor size, and the surgeon were independent predictors of mastectomy. Surgeon A had a mastectomy rate of 30.5% (50/164), surgeon B 26.9% (43/160) respectively, and surgeon C had a mastectomy rate of 15.8% (27/171), p = 0.005. Patients, who had surgery performed by surgeon A or surgeon B were 2.34 [95% confidence interval (CI): 1.38-3.97, p < 0.005] respectively 1.96 (95% CI: 1.14-3.36, p = 0.01) times as likely to have a mastectomy than patients who had surgery performed by surgeon C. Even in a certified breast center with specialized breast surgeons the surgeon is an independent risk factor of mastectomy, as the tumor criteria are given at the time of diagnosis.

摘要

本研究在一家认证乳腺中心调查了乳房切除术的预测因素,主要影响因素是外科医生。共分析了663例患者的乳房切除率。纳入的患者为T1和T2期肿瘤患者,由三位专门的乳腺外科医生之一进行手术,每位医生每年至少有50例新的乳腺癌病例。多因素分析显示,肿瘤中心定位、淋巴结阳性状态、非单灶性、肿瘤体积大以及外科医生是乳房切除术的独立预测因素。外科医生A的乳房切除率为30.5%(50/164),外科医生B为26.9%(43/160),外科医生C为15.8%(27/171),p = 0.005。由外科医生A或外科医生B进行手术的患者进行乳房切除术的可能性分别是由外科医生C进行手术患者的2.34倍[95%置信区间(CI):1.38 - 3.97,p < 0.005]和1.96倍(95% CI:1.14 - 3.36,p = 0.01)。即使在有专门乳腺外科医生的认证乳腺中心,外科医生仍是乳房切除术的独立风险因素,因为肿瘤标准在诊断时已确定。

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