Safran D, Welch J, Rezuke W
Department of Surgery, Hartford Hospital, CT 06115.
Arch Surg. 1991 Jul;126(7):904-8. doi: 10.1001/archsurg.1991.01410310114018.
Inflammatory pseudotumors are uncommon benign lesions that have been found in numerous organ systems. However, their appearance within the spleen is decidedly rare. Grossly, pseudotumors appear as well-circumscribed, encapsulated masses, while microscopic examination reveals a polymorphous inflammatory cell infiltrate occurring variably with granulomatous reaction, fibrosis, and cell necrosis. Because they often present either as unexplained, asymptomatic masses or with vague constitutional symptoms, splenic inflammatory pseudotumors can raise suspicion for a primary splenic neoplasm, such as lymphoma. Splenectomy is the treatment of choice.
炎性假瘤是一种罕见的良性病变，见于众多器官系统。然而，其出现在脾脏中实属罕见。大体上，假瘤表现为边界清晰、有包膜的肿块，而显微镜检查显示有多形性炎性细胞浸润，并伴有不同程度的肉芽肿反应、纤维化和细胞坏死。由于脾脏炎性假瘤通常表现为不明原因的无症状肿块或伴有模糊的全身症状，可能会让人怀疑是原发性脾脏肿瘤，如淋巴瘤。脾切除术是首选的治疗方法。
