Psooy Karen
The Division of Pediatric Urology, Winnipeg Children's Hospital, Winnipeg, Man.
Can Urol Assoc J. 2007 Jun;1(2):113-6.
To determine whether the current indications for the long-term urological follow-up of children with multicystic dysplastic kidneys (MCDKs) are supported by the literature.
The membership of the Pediatric Urologists of Canada was surveyed to determine if long-term urological follow-up was being performed, and if so, for what indications. A literature search using PubMed, EMBASE and a Conference Papers Index was performed to determine whether the indications listed were supported by the literature.
A response rate of 72% was achieved for the survey, with most respondents following children with MCDK long-term. The main indications for long-term follow-up were the increased risk of Wilms' tumour (54%) and hypertension (32%), observation of the contralateral kidney (43%) and involution of the MCDK (36%). The literature search did not support long-term urological follow-up for any of these indications, provided unilateral MCDK was an isolated genitourinary abnormality. Although it is rare, a primary care physician could monitor for hypertension.
Long-term urological follow-up of children with "simple MCDK" is not supported by the literature, provided the diagnosis has been confirmed with a follow-up renal ultrasound at 12-24 months. Blood pressure monitoring by a primary care physician is recommended.
确定文献是否支持目前对多囊性发育不良肾(MCDK)患儿进行长期泌尿外科随访的指征。
对加拿大儿科泌尿外科医生进行调查,以确定是否正在进行长期泌尿外科随访,若进行随访,其指征是什么。利用PubMed、EMBASE和会议论文索引进行文献检索,以确定所列指征是否有文献支持。
调查的回复率为72%,大多数受访者对MCDK患儿进行长期随访。长期随访的主要指征是肾母细胞瘤风险增加(54%)和高血压(32%)、对侧肾脏的观察(43%)以及MCDK的退化(36%)。文献检索不支持对这些指征中的任何一项进行长期泌尿外科随访,前提是单侧MCDK是孤立的泌尿生殖系统异常。虽然罕见,但初级保健医生可监测高血压。
若在12 - 24个月时通过肾脏超声随访确诊,文献不支持对“单纯MCDK”患儿进行长期泌尿外科随访。建议由初级保健医生监测血压。