Eaton S, Brent S, Shah N, Masters G
Northumbria Healthcare NHS Foundation Trust, North Shields, Tyne and Wear, UK.
Diabet Med. 2008 Jun;25(6):738-42. doi: 10.1111/j.1464-5491.2008.02429.x.
To establish if a relationship exists between the prescribing costs of diabetes treatments and the achievement of Quality and Outcome Framework DM6 standards of glycaemic control.
A retrospective cross-sectional study of all 92 primary care organizations in the north of England comparing net ingredient cost of diabetes treatments, corrected for diabetic population, with the percentage of patients achieving HbA(1c) < 7.4% (Quality and Outcome Framework DM6 indicator).
The overall net ingredient cost for diabetes treatments varies from pound 225 to pound 382 per person per year. On regression analysis, expenditure on all diabetes treatments, on glitazones or on blood glucose test strips have no significant impact upon the percentage of people achieving an HbA(1c) < 7.4%. There is an inverse relationship between spending on analogue insulins and target achievement (r = -0.08, P = 0.001).
At primary care organization level, there is no association between weighted expenditure on diabetes treatments and achievement of glycaemic control targets. Although there are limitations to what can be inferred from analyses of this type, these data support a judicious and carefully directed approach to the use of newer, more expensive treatments until clear evidence of added benefit is forthcoming.
确定糖尿病治疗的处方成本与达到血糖控制的质量与结果框架DM6标准之间是否存在关联。
对英格兰北部所有92个初级保健机构进行回顾性横断面研究,比较经糖尿病患者人数校正后的糖尿病治疗净成分成本与HbA(1c)<7.4%(质量与结果框架DM6指标)的患者百分比。
糖尿病治疗的总体净成分成本为每人每年225英镑至382英镑不等。回归分析显示,所有糖尿病治疗、格列酮类药物或血糖试纸的支出对HbA(1c)<7.4%的患者百分比没有显著影响。类似物胰岛素的支出与目标达成之间存在负相关(r = -0.08,P = 0.001)。
在初级保健机构层面,糖尿病治疗的加权支出与血糖控制目标的达成之间没有关联。尽管从这类分析中能推断出的内容存在局限性,但这些数据支持在有明确的额外益处证据出现之前,对使用更新、更昂贵的治疗方法采取明智且谨慎的定向方法。