Xue Jing, Gao Peiyi, Wang Xiaochun, Liao Xiaoling, Wang Yilong, Wang Yongjun
Department of Neuroradiology, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Neurol Res. 2008 May;30(4):337-40. doi: 10.1179/174313208X300297.
The ability to rapidly and accurately evaluate the location and extent of hyperacute brain ischemia is of major clinical importance. Herein, we aimed to develop imaging criteria to classify the ischemic lesion by computed tomography (CT) perfusion (CTP) and CT angiography (CTA) in hyperacute ischemic stroke patient. Non-contrast-enhanced CT, CTP and CTA were performed in patients with symptoms of hyperacute stroke lasting <8 hours. According to the volume of infarct core, ischemic penumbra and vessel status, three ischemic lesion types were defined. Twenty-six patients were included in our study. Among them, ten patients were classified into severe group, 15 patients were classified into mild group and one patient was classified into reversible group. In acute stroke patients, the ischemic lesion typing may assist in individualizing therapeutic decisions for patients by possibly extending the window for giving thrombolytics beyond the current 3 hour limit.
快速准确地评估超急性脑缺血的位置和范围的能力具有重要的临床意义。在此，我们旨在制定影像学标准，通过计算机断层扫描（CT）灌注（CTP）和CT血管造影（CTA）对超急性缺血性中风患者的缺血性病变进行分类。对症状持续时间小于8小时的超急性中风患者进行了非增强CT、CTP和CTA检查。根据梗死核心体积、缺血半暗带和血管状态，定义了三种缺血性病变类型。我们的研究纳入了26例患者。其中，10例患者被分类为重度组，15例患者被分类为轻度组，1例患者被分类为可逆组。在急性中风患者中，缺血性病变分型可能通过将溶栓治疗的时间窗延长至目前的3小时限制之外，有助于为患者制定个体化的治疗决策。
