Ferreira R C, Serra J, Bernardes L, Abreu J, Ferreira L, Antunes E, Oliveira M, Quininha J, Gonçalves J M, Ferreira M G
Serviço de Cardiologia, Hospital de Santa Marta.
Rev Port Cardiol. 1991 Mar;10(3):249-56.
To analyze the relation between characteristics of symptom-limited treadmill exercise stress test, after acute myocardial infarction (MI) and coronariographic results (number of diseased vessels). Both tests were performed before hospital discharge.
Retrospective study with comparative analysis between variable defined groups.
From 232 patients interned in the department of Cardiology of Hospital de Santa Marta with a first acute MI, a population of 112 patients submitted to exercise stress test and coronary angiography before discharge were selected (aged 29 to 69 years).
Symptom-limited treadmill exercise stress tests were performed according to Bruce protocol, with no heart-rate limitation. The following parameters were analyzed: Stress test duration (DUR); Double product variation (varDP); Metabolic equivalent units (METS); Maximal heart rate (FCmax); Percentage of the maximal reached heart rate (% FCmax); Incidence of ST segment depression (InfST); Maximal ST segment depression (Max-InfST); Onset minute of ST segment depression (MinInfST); Heart rate at the onset of ST segment depression (FCInfST); Double product at the onset of ST segment depression (DPInfST); Recovery minute of ST segment depression (MinRInfST); Onset minute of angina (MinAng); Heart rate at the onset of angina (FCAng); Double product at the onset of angina (DPAng).
Statistical significant differences were obtained between coronariographic groups concerning the following parameters: DUR: 1-vessel/3-vessel P = 0.02; VarDP: 1-vessel/3-vessel p = 0.008, 2-vessel/3-vessel p = 0.004; METS: 1-vessel/3-vessel p = 0.01. No differences were seen between anterior and inferior myocardial infarctions regarding all the stress test parameters. However in patients with anterior MI significant differences were obtained concerning the following variables: VarDP: 1-vessel/2-vessel p = 0.02; InfraST: 1-vessel/2-vessel p = 0.006, 1-vessel/3-vessel p = 0.03; MaxInfST: 1-vessel/2-vessel p = 0.01, 1-vessel/3-vessel p = 0.0006; Angina: 1-vessel/2-vessel p = 0.0005, 1-vessel/3-vessel p = .001. In inferior myocardial infarctions only the stress duration differed between 1-vessel and 3-vessel groups (p = 0.003).
Symptom-limited treadmill exercise stress tests, safely performed in our institution, were an important method for post MI evaluation and allowed the diagnosis of a great number of patients with residual ischemia. Statistical significant differences were found in ergometric parameters, between coronariographic groups (defined by the number of diseased vessels), emphasising the importance of stress tolerance analysis.
分析急性心肌梗死(MI)后症状限制平板运动负荷试验特征与冠状动脉造影结果(病变血管数量)之间的关系。两项检查均在出院前进行。
对定义的变量组进行比较分析的回顾性研究。
从圣玛尔塔医院心内科收治的232例首次急性心肌梗死患者中,选取112例在出院前接受运动负荷试验和冠状动脉造影的患者(年龄29至69岁)。
根据布鲁斯方案进行症状限制平板运动负荷试验,无心率限制。分析以下参数:运动负荷试验持续时间(DUR);双乘积变化(varDP);代谢当量单位(METS);最大心率(FCmax);达到最大心率的百分比(%FCmax);ST段压低发生率(InfST);最大ST段压低(Max-InfST);ST段压低开始分钟数(MinInfST);ST段压低开始时的心率(FCInfST);ST段压低开始时的双乘积(DPInfST);ST段压低恢复分钟数(MinRInfST);心绞痛开始分钟数(MinAng);心绞痛开始时的心率(FCAng);心绞痛开始时的双乘积(DPAng)。
冠状动脉造影组之间在以下参数上存在统计学显著差异:DUR:单支血管病变/三支血管病变P = 0.02;varDP:单支血管病变/三支血管病变p = 0.008,双支血管病变/三支血管病变p = 0.004;METS:单支血管病变/三支血管病变p = 0.01。在前壁和下壁心肌梗死患者的所有运动负荷试验参数方面未发现差异。然而,在前壁心肌梗死患者中,以下变量存在显著差异:varDP:单支血管病变/双支血管病变p = 0.02;InfraST:单支血管病变/双支血管病变p = 0.006,单支血管病变/三支血管病变p = 0.03;MaxInfST:单支血管病变/双支血管病变p = 0.01,单支血管病变/三支血管病变p = 0.0006;心绞痛:单支血管病变/双支血管病变p = 0.0005,单支血管病变/三支血管病变p = 0.001。在下壁心肌梗死患者中,仅单支血管病变和三支血管病变组之间的运动负荷持续时间存在差异(p = 0.003)。
在我们机构安全进行的症状限制平板运动负荷试验是心肌梗死后评估的重要方法,能够诊断大量有残余缺血的患者。在冠状动脉造影组(根据病变血管数量定义)之间的运动参数方面发现了统计学显著差异,强调了运动耐量分析的重要性。