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生物医学研究及圈养环境中的刺豚鼠(刺豚鼠属)

The agouti (Dasyprocta sp) in biomedical research and captivity.

作者信息

Baas E J, Potkay S, Bacher J D

出版信息

Lab Anim Sci. 1976 Oct;26(5):788-96.

PMID:185455
Abstract

Agoutis (Dasyprocta sp) are hystricomorph rodents belonging to the family Dasyproctidae. Utilization of agoutis in a research program of the National Institutes of Health necessitated the development of suitable methods for feeding, housing and collecting blood. The rodents were maintained successfully in conventional dog cages and kennels, and thrived on a diet of primate diet and apples. Physical examinations and periodic blood collections were best performed while agoutis were sedated with ketamine HCl (42-83 mg/kg, intramuscularly). Satisfactory sites for blood sampling were the cephalic, saphenous and jugular veins. Hematologic and serum chemical values established for the agouti were similar to those found in other rodents. Experimentally induced and naturally occurring diseases of agoutis were reviewed.

摘要

刺豚鼠(Dasyprocta sp)是属于刺豚鼠科的豪猪亚目啮齿动物。在美国国立卫生研究院的一项研究项目中使用刺豚鼠,需要开发合适的饲养、圈养和采血方法。这些啮齿动物成功地饲养在传统的狗笼和犬舍中,并以灵长类动物饲料和苹果为食而茁壮成长。在使用盐酸氯胺酮(42 - 83毫克/千克,肌肉注射)使刺豚鼠镇静时,进行体格检查和定期采血效果最佳。满意的采血部位是头静脉、隐静脉和颈静脉。为刺豚鼠确定的血液学和血清化学值与其他啮齿动物相似。对刺豚鼠的实验性诱发疾病和自然发生疾病进行了综述。

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