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[流行地区爆发后亚临床皮肤利什曼病病例的血清学调查]

[Serological investigation of subclinical cutaneous leishmaniasis cases following an outbreak in an endemic area].

作者信息

Arraes Sandra Mara Alessi Aristides, Marini Mirela Teixeira, Martello Daiane, Silveira Thaís Gomes Verzignassi, Lonardoni Maria Valdrinez Campana, Nanni Marcos Rafael

机构信息

Departamento de Análises Clínicas, Universidade Estadual de Maringá, Maringá, PR.

出版信息

Rev Soc Bras Med Trop. 2008 Mar-Apr;41(2):205-8. doi: 10.1590/s0037-86822008000200016.

DOI:10.1590/s0037-86822008000200016
PMID:18545847
Abstract

Subclinical cases of cutaneous leishmaniasis were investigated in a district of Maringá, State of Paraná, by means of the indirect immunofluorescence reaction and enzyme immunoassay. Among the 130 samples analyzed, one presented titer 40 and three presented titer 20 in the indirect immunofluorescence reaction, while 11 samples were positive in the enzyme immunoassay reaction. These data suggest that subclinical cases exist at this locality.

摘要

通过间接免疫荧光反应和酶免疫测定法，对巴拉那州马林加市一个地区的皮肤利什曼病亚临床病例进行了调查。在分析的130份样本中，1份在间接免疫荧光反应中的滴度为40，3份的滴度为20，而11份样本在酶免疫测定反应中呈阳性。这些数据表明该地区存在亚临床病例。

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Development of an Electrochemical Immunosensor for Specific Detection of Visceral Leishmaniasis Using Gold-Modified Screen-Printed Carbon Electrodes.基于金修饰丝网印刷碳电极的电化学免疫传感器特异性检测内脏利什曼病的研究。
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Detection of DNA from Leishmania (Viannia): accuracy of polymerase chain reaction for the diagnosis of cutaneous leishmaniasis.检测利什曼原虫（Viannia）DNA：聚合酶链反应诊断皮肤利什曼病的准确性。
PLoS One. 2013 Jul 5;8(7):e62473. doi: 10.1371/journal.pone.0062473. eCollection 2013.