Broggi Giovanni, Ferroli Paolo, Franzini Angelo
Department of Neurosurgery Fondazione Istituto Neurologico Carlo Besta, Milan, Italy.
Neurol Sci. 2008 May;29 Suppl 1:S79-82. doi: 10.1007/s10072-008-0893-6.
Trigeminal neuralgia is an invalidating disease when become drug-resistant. The only possible treatment is surgery with different modalities, percutaneous, open surgery or radiosurgery. The thirty years experience at the Fondazione Istituto Neurologico C. Besta, Milano, Italy suggests that these surgical strategies are successful in pain control in short and long term period in more than 90% of cases, with a low rate of side effects and high improvement of quality of life. The type of surgery should be tailored on the particular patient considering age, general physical condition, neuroradiological assessment in which MRI with dedicated sequences are mandatory, and also patient's attitude.
三叉神经痛在出现耐药性时是一种使人衰弱的疾病。唯一可能的治疗方法是采用不同方式的手术，包括经皮手术、开放手术或放射外科手术。意大利米兰神经病学研究所C. 贝斯塔基金会三十年的经验表明，这些手术策略在90%以上的病例中能在短期和长期有效控制疼痛，副作用发生率低，生活质量有很大改善。手术类型应根据特定患者的年龄、一般身体状况、神经放射学评估（其中必须使用专用序列的MRI）以及患者的态度来量身定制。
