Milanini M N, D'onofrio P, Melani Novelli A M, Dabizzi S, Cozzi C, Evangelisti P, Quitadamo L, Noci I
Center of Human Reproduction Physiopathology, University of Florence, Florence, Italy.
Minerva Ginecol. 2008 Jun;60(3):203-7.
The aim of the work was to compare two different techniques, local anaesthesia versus continuous intravenous administration of remifentanil for oocyte retrieval. The impact on the medical assisted procreation (PMA) procedures in terms of number and quality of oocytes collected was evaluated.
The experimental design was a retrospective study which compared two different techniques, local anaesthesia versus continuous intravenous administration of remifentanil. 548 women with the same infertility duration and ovarian reserve were classified in two groups of 274 women each, that underwent to oocytes retrieval with intravenous infusion of remifentanil (first group) or with local anesthesia (second group).
The analysis showed that the intravenous infusion of remifentanil doesn't interfere in the quality of oocytes retrieved and embryo score.
The administration of intravenous remifentanil makes easier the pick-up of oocytes because women had no pain during the procedure. In this way, it was possible to recover more oocytes and to verify that the drug doesn't interfere with the exitus of the techniques. For these reasons we decided to continue in using intravenous infusion of remifentanil for the retrieval of oocytes.
本研究旨在比较两种不同的技术，即局部麻醉与瑞芬太尼持续静脉给药用于取卵手术。评估了在收集的卵母细胞数量和质量方面对辅助生殖技术（PMA）程序的影响。
实验设计为一项回顾性研究，比较了两种不同的技术，即局部麻醉与瑞芬太尼持续静脉给药。将548名不孕时间和卵巢储备相同的女性分为两组，每组274名女性，分别接受瑞芬太尼静脉输注（第一组）或局部麻醉（第二组）进行取卵手术。
分析表明，瑞芬太尼静脉输注不会干扰所取卵母细胞的质量和胚胎评分。
静脉注射瑞芬太尼使取卵更容易，因为女性在手术过程中没有疼痛。通过这种方式，可以回收更多的卵母细胞，并验证该药物不会干扰技术的结果。出于这些原因，我们决定继续使用瑞芬太尼静脉输注进行取卵。
