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16例艾滋病患者感染新型隐球菌病

[16 cases of infection by Cryptococcosis neoformans in patients with AIDS].

作者信息

Castro Guardiola A, Ocaña Rivera I, Gasser Laguna I, Ruiz Camps I, Planes Reig A M, Juste Sánchez C, Martínez Vázquez J M

机构信息

Servicio de Medicina Interna, Universitat Autònoma de Barcelona.

出版信息

Enferm Infecc Microbiol Clin. 1991 Feb;9(2):90-4.

PMID:1854856
Abstract

Sixteen patients with AIDS (6% of the total AIDS patients) who had infection by Cryptococcus neoformans were studied. Most of these patients (94%) had cryptococcal meningitis. Only 50% of the cases showed clinical manifestations of neurological involvement. Blood cultures and antigen level measurement were the diagnostic techniques with best results due to their high percentage of positivity. Sixty nine percent of patients survived the acute phase of the infection and only 3 of those who died in this period showed evidence of active infection patients by the fungus.

摘要

对16例感染新型隐球菌的艾滋病患者(占艾滋病患者总数的6%)进行了研究。这些患者中的大多数(94%)患有隐球菌性脑膜炎。只有50%的病例表现出神经受累的临床表现。血培养和抗原水平检测是诊断效果最佳的技术,因其阳性率高。69%的患者在感染急性期存活下来,在此期间死亡的患者中只有3例显示有该真菌的活动性感染迹象。

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