Tran C, Roulet M, Guex E, Coti Bertrand P
Service de Médecine Interne, CHUV, Lausanne.
Praxis (Bern 1994). 2008 Mar 5;97(5):261-4. doi: 10.1024/1661-8157.97.5.261.
Acquired pressure ulcer is associated with significant human, economic and functional consequences. Its prevalence varies between 3 and 23% in a community hospital and between 7 and 54% in an elderly home residency. Pressure ulcer healing is a complex process which involves numerous cellular and molecular mechanisms. An altered nutritional status is a contributing factor in the development of pressure ulcers and the delay in pressure ulcer healing. The key to management of undernutrition is screening and early intervention. According to the gravity of undernutrition, various degrees of intervention will be required. Systematic oral supplementation with various nutrients may provide benefit in the prevention of pressure ulcers, but further studies have to be completed in human subjects prior to being recommended for the treatment of pressure ulcers.
获得性压疮会带来严重的人体、经济和功能方面的后果。其患病率在社区医院为3%至23%，在老年家庭住所为7%至54%。压疮愈合是一个复杂的过程，涉及众多细胞和分子机制。营养状况改变是压疮发生和愈合延迟的一个促成因素。营养不良管理的关键是筛查和早期干预。根据营养不良的严重程度，将需要不同程度的干预。系统口服各种营养素可能对预防压疮有益，但在被推荐用于治疗压疮之前，还必须在人体受试者中完成进一步的研究。
