Sudano I, Périat D, Noll G
Herz-Kreislauf-Zentrum, Kardiologie, Universitätsspital Zürich.
Praxis (Bern 1994). 2008 Apr 2;97(7):375-80. doi: 10.1024/1661-8157.97.7.375.
The endocannabinoid system is a physiological system, which is responsible for the control of glucose and lipid-metabolism, as well as for the regulation of the body weight. The endocannabinoid receptors are distributed both in the central and peripher nervous system. Different studies provide evidence that an hyperactive endocannabinoid system is involved in the development of different cardiovascular risk factors. The pharmacological blockade of these cannabinoid receptors may represent a new approach for cardiometabolic risk management.
内源性大麻素系统是一种生理系统,负责控制葡萄糖和脂质代谢以及调节体重。内源性大麻素受体分布于中枢神经系统和外周神经系统。不同的研究表明,内源性大麻素系统过度活跃与多种心血管危险因素的发生有关。对这些大麻素受体进行药物阻断可能是一种新的心脏代谢风险管理方法。