Michelotti Ambra, Farella M, Stellato A, Martina R, De Laat Antoon
Department of Orthodontics, School of Dentistry, University of Naples "Federico II", Naples, Italy.
J Orofac Pain. 2008 Spring;22(2):139-45.
To compare the tactile detection threshold, the filament-prick pain detection threshold, the pressure pain threshold, and the pressure pain tolerance detection threshold at multiple measuring points in the orofacial region and at the thenar muscle of symptom-free subjects and patients with myofascial pain of the masticatory muscles.
Twenty patients (age range: 25 to 55 years) and 20 healthy subjects (age range: 25 to 55 years) were recruited. The tactile detection threshold and the filament prick-pain detection threshold were measured at the cheek skin overlying the central part of the left and right masseter muscles, at the right thenar muscle and at the tip of the tongue, using Semmes-Weinstein monofilaments. The pressure pain threshold and the pressure pain tolerance threshold were measured at the central part of the masseter muscle and on the thenar muscle, using a pressure algometer. The intensity of pain perceived during the assessment of filament prick-pain detection threshold, pressure pain threshold, and the pressure pain tolerance threshold was scored on visual analog scales.
The tongue tip had the lowest filament prick-pain detection thresholds as compared to the other sites. Filament prick-pain detection thresholds of the tongue and thumb sites were significantly lower in myofascial pain patients than in controls. Pressure pain thresholds of the masseter and thenar muscles were significantly lower in patients with myofascial pain than in control subjects whereas pressure pain tolerance thresholds did not differ significantly between patients and controls.
The findings of the present study show topographic variations in the pain responses to different stimulus modalities. Different pain responses were also found between patients with myofascial pain and control subjects and were interpreted to support theories of centrally mediated pain for temporomandibular disorders.
比较无症状受试者和咀嚼肌肌筋膜疼痛患者在口面部区域多个测量点以及大鱼际肌处的触觉检测阈值、单丝刺痛疼痛检测阈值、压痛阈值和压痛耐受检测阈值。
招募了20名患者(年龄范围:25至55岁)和20名健康受试者(年龄范围:25至55岁)。使用Semmes-Weinstein单丝在覆盖左右咬肌中部的脸颊皮肤、右侧大鱼际肌和舌尖处测量触觉检测阈值和单丝刺痛疼痛检测阈值。使用压力痛觉计在咬肌中部和大鱼际肌处测量压痛阈值和压痛耐受阈值。在评估单丝刺痛疼痛检测阈值、压痛阈值和压痛耐受阈值期间所感知的疼痛强度采用视觉模拟量表进行评分。
与其他部位相比,舌尖的单丝刺痛疼痛检测阈值最低。肌筋膜疼痛患者舌头和拇指部位的单丝刺痛疼痛检测阈值显著低于对照组。肌筋膜疼痛患者咬肌和大鱼际肌的压痛阈值显著低于对照受试者,而患者和对照组之间的压痛耐受阈值没有显著差异。
本研究结果显示了对不同刺激方式的疼痛反应存在地形学差异。在肌筋膜疼痛患者和对照受试者之间也发现了不同的疼痛反应,这被解释为支持颞下颌关节紊乱症中枢介导疼痛的理论。