Chen Ying-Dan, Tang Lin-Hua, Xu Long-Qi
National Institute of Parasitic Diseases, Chinese Center for Diseases Control and Prevention, Shanghai 200025, China.
Biomed Environ Sci. 2008 Apr;21(2):173-9. doi: 10.1016/S0895-3988(08)60025-2.
To carry out national surveys for ascertaining the current status and trends of soil-transmitted nematode infections in China, providing scientific basis for further developing control strategies.
In 1988-1992 (hereinafter abbreriated as "survey in 1990"), a stratified cluster random sampling method was used in the survey. In 2001-2004 (hereinafter abbreriated as "survey in 2003"), in order to compare with the survey in 1990, two-characteristic stratified cluster random sampling method was used and 687 investigation spots were sampled from the 2848 spots selected in the survey in 1990. Kato-Katz thick smear method was used to examine the eggs of soil-transmitted nematodes in fecal samples.
The prevalence rates were 53.6% and 19.6% for soil-transmitted nematodes, 14.6% and 6.120% for hookworms, 44.6% and 12.7% for Ascaris lumbricoides, 17.4% and 4.630% for Trichuris trichiura in survey 1990 and survey 2003, respectively. The prevalence rates of soil-transmitted nematodes were higher in 13 provinces than the average level in China in the survey in 1990, and higher in 8 provinces than the average level in the survey in 2003. The prevalence of hookworms, Ascaris lumbricoides, Trichuris trichiura and the overall prevalence of soil-transmitted nematodes were higher in females than in males. It is estimated from the results of survey in 2003 that the number of persons with soil-transmitted nematode infections in the country is about 129 million, less than that in the survey in 1990.
The prevalence of soil-transmitted nematodes has declined considerably but is still relatively high in some provinces and autonomous regions. Control activities and socioeconomic development may have contributed to the decreased prevalence.
开展全国性调查，以确定中国土源性线虫感染的现状和趋势，为进一步制定防控策略提供科学依据。
1988 - 1992年（以下简称“1990年调查”），调查采用分层整群随机抽样方法。2001 - 2004年（以下简称“2003年调查”），为与1990年调查作比较，采用二阶段分层整群随机抽样方法，从1990年调查选取的2848个调查点中抽取687个调查点。采用改良加藤厚涂片法检查粪便中土源性线虫虫卵。
1990年调查和2003年调查中土源性线虫感染率分别为53.6%和19.6%，钩虫感染率分别为14.6%和6.120%，蛔虫感染率分别为44.6%和12.7%，鞭虫感染率分别为17.4%和4.630%。1990年调查中，13个省份的土源性线虫感染率高于全国平均水平，2003年调查中有8个省份高于全国平均水平。钩虫、蛔虫、鞭虫感染率及土源性线虫总体感染率女性高于男性。根据2003年调查结果估计，全国土源性线虫感染人数约1.29亿，低于1990年调查结果。
土源性线虫感染率虽有大幅下降，但在部分省（区）仍处于较高水平。防控措施及社会经济发展可能促使感染率下降。
