Loh K Y, Shong H K
Department of Family Medicine, International Medical Universiti Malaysia, Jalan Rasah, Seremban 70300, Negeri Sembilan.
Med J Malaysia. 2007 Oct;62(4):355-7; quiz 358.
The incidence of osteoporosis is increasing worldwide. It has great impact on the life of the elderly population. The most significant medical consequence of osteoporosis is fragility fracture which without proper treatment will cause severe medical and psychosocial complications. The overall cost in managing osteoporosis and its related fractures is escalating. Using bone densitometry to measure bone mineral density is useful in the diagnosis of osteoporosis but it is costly and not feasible in the community. Drugs such as estrogen replacement, raloxifene and calcitonin are effective in prevention and treatment of osteoporosis but they are also expensive. Identifying modifiable risk factors such as smoking, lack of exercise, low dietary calcium and vitamin D intake and healthy life style remain strategy in the primary prevention of osteoporosis in the community.
骨质疏松症在全球范围内的发病率正在上升。它对老年人群的生活有很大影响。骨质疏松症最严重的医学后果是脆性骨折,若不进行适当治疗,将导致严重的医学和心理社会并发症。管理骨质疏松症及其相关骨折的总体成本正在不断上升。使用骨密度测定法测量骨矿物质密度对骨质疏松症的诊断很有用,但成本高昂且在社区中不可行。雌激素替代疗法、雷洛昔芬和降钙素等药物在预防和治疗骨质疏松症方面有效,但也很昂贵。识别可改变的风险因素,如吸烟、缺乏运动、饮食中钙和维生素D摄入量低以及健康的生活方式,仍然是社区中骨质疏松症一级预防的策略。