Jha Vivekanand
Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Perit Dial Int. 2008 Jun;28 Suppl 3:S36-41.
With its ambulatory nature and freedom from complicated and expensive technology, chronic peritoneal dialysis (PD) is the ideal renal replacement therapy for resource-poor India. Despite being available for more than 15 years, PD has been limited in its growth because of economic factors, inadequate government policies, nephrologist bias, and lack of adequate pre-dialysis care. The number of patients initiated on therapy has increased in recent years, but the number of early dropouts remains high. Single-center studies suggest that contributors to poor outcome include gram-negative peritonitis, malnutrition, and failure to increase the dialysis dose as residual renal function declines. Development of a national PD registry and increased educational activities to position PD as part of integrated therapy for end-stage kidney disease would improve utilization of the PD modality.
慢性腹膜透析(PD)具有非卧床性质且无需复杂昂贵的技术,对于资源匮乏的印度而言,它是理想的肾脏替代疗法。尽管PD已应用超过15年,但由于经济因素、政府政策不完善、肾病学家的偏见以及缺乏充分的透析前护理,其发展一直受限。近年来开始接受治疗的患者数量有所增加,但早期退出治疗的人数仍然居高不下。单中心研究表明,导致不良预后的因素包括革兰氏阴性腹膜炎、营养不良以及随着残余肾功能下降未能增加透析剂量。建立全国性的腹膜透析登记系统并加强教育活动,将腹膜透析定位为终末期肾病综合治疗的一部分,这将提高腹膜透析方式的利用率。