Lehman Ronald A, Lenke Lawrence G, Keeler Kathryn A, Kim Yongjung J, Buchowski Jacob M, Cheh Gene, Kuhns Craig A, Bridwell Keith H
Walter Reed Army Medical Center, USA.
Spine (Phila Pa 1976). 2008 Jun 15;33(14):1598-604. doi: 10.1097/BRS.0b013e318178872a.
Preoperative review of a prospective study, single institution, consecutive series. OBJECTIVE.: To analyze the intermediate-term follow-up of consecutive adolescent idiopathic scoliosis (AIS) patients treated with pedicle screw constructs.
There have been no reports of the intermediate-term findings in North America following posterior spinal fusion with the use of pedicle screw-only constructs.
One hundred and fourteen consecutive patients having a minimum 3-year follow-up (mean 4.8 +/- 1.1; range, 3.0-7.3 years) with AIS were evaluated. The average age at surgery was 14.9 +/- 2.2 years. Radiographic measurements included preoperative (Preop), postoperative (PO), 2-year (2 years), and final follow-up (FFU). A chart review evaluated PFTs, Scoliosis Research Society scores, presence of thoracoplasty, Risser sign, Lenke classification, and complications.
The most frequent curve pattern was Lenke type 1 (45.6%), followed by type 3 (21.9%). The average main thoracic curve measured 59.2 degrees +/- 12.2 SD Preop, and corrected to 16.8 degrees +/- 9.9 PO (P < 0.0001). Sagittal thoracic alignment (T5-T12) decreased from 25.8 degrees to 15.5 degrees at FFU (P = 0.05). Nash-Moe grading for apical vertebral rotation (AVR) in the proximal thoracic curve decreased from 2.0 Preop to 1.1 at FFU (P < 0.0001), and AVR in the thoracolumbar/lumbar spine decreased from 1.6 Preop to 1.1 at FFU (P < 0.0001). Importantly, the horizontalization of the subjacent disc measured -8.3 degrees Preop which decreased to -0.9 degrees PO (P < 0.001). PFT follow-up averaged 2.4 years with a 7.1% improvement in FVC (P = 0.004) and 8.8% in FEV1 (P < 0.0001). SRS scores averaged 83.0% at latest follow-up. Age, gender, Risser sign, or complications did not have a significant effect on outcomes. There were 2 cases of adding-on, 3 late onset infections, 1 with a single pseudarthrosis, but no neurologic complications.
This is the largest (N = 114), consecutive series of North American patients with AIS treated with pedicle screws having a minimum of 3-year follow-up. The average curve correction was 68% for the main thoracic, 50% for the proximal thoracic, and 66% for the thoracolumbar/lumbar curve at final follow-up.
一项前瞻性研究的术前回顾,单机构,连续病例系列。目的:分析采用椎弓根螺钉内固定治疗的连续性青少年特发性脊柱侧凸(AIS)患者的中期随访情况。
北美地区尚无关于单纯使用椎弓根螺钉进行后路脊柱融合术后中期结果的报道。
对114例接受至少3年随访(平均4.8±1.1年;范围3.0 - 7.3年)的AIS患者进行评估。手术时的平均年龄为14.9±2.2岁。影像学测量包括术前(Preop)、术后(PO)、2年(2 years)及末次随访(FFU)。通过查阅病历评估肺功能测试(PFTs)、脊柱侧凸研究学会(SRS)评分、胸廓成形术情况、Risser征、Lenke分型及并发症。
最常见的侧弯类型为Lenke 1型(45.6%),其次是3型(21.9%)。术前主胸弯平均角度为59.2°±12.2°标准差,术后矫正至16.8°±9.9°(P < 0.0001)。末次随访时胸段矢状面排列(T5 - T12)从25.8°降至15.5°(P = 0.05)。近端胸弯顶椎旋转(AVR)的Nash - Moe分级从术前的2.0降至末次随访时的1.1(P < 0.0001),胸腰段/腰段脊柱的AVR从术前的1.6降至末次随访时的1.1(P < 0.0001)。重要的是,相邻椎间盘的水平化术前为 - 8.3°,术后降至 - 0.9°(P < 0.001)。PFT随访平均2.4年,用力肺活量(FVC)提高了7.1%(P = 0.004),第1秒用力呼气容积(FEV1)提高了8.8%(P < 0.0001)。末次随访时SRS评分平均为83.0%。年龄、性别、Risser征或并发症对结果均无显著影响。有2例追加手术,3例迟发性感染,1例单发假关节形成,但无神经并发症。
这是北美地区最大规模(N = 114)的连续性AIS患者系列研究,采用椎弓根螺钉治疗且至少随访3年。末次随访时主胸弯平均矫正率为68%,近端胸弯为50%,胸腰段/腰段侧弯为6