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Lenke 5C 型青少年特发性脊柱侧凸的手术治疗比较:前路双棒与后路椎弓根固定术:两种实践的比较。

Comparison of surgical treatment in Lenke 5C adolescent idiopathic scoliosis: anterior dual rod versus posterior pedicle fixation surgery: a comparison of two practices.

机构信息

Department of Orthopaedics, Spine Austin, 3001 Beecaves Road, Austin, TX 78746, USA.

出版信息

Spine (Phila Pa 1976). 2009 Aug 15;34(18):1942-51. doi: 10.1097/BRS.0b013e3181a3c777.

Abstract

STUDY DESIGN

Multicenter analysis of 2 groups of patients surgically treated for Lenke 5C adolescent idiopathic scoliosis (AIS).

OBJECTIVE

Compare patients with Lenke 5C scoliosis surgically treated with anterior spinal fusion with dual rod instrumentation and anterior column support with patients surgically treated with posterior release and pedicle screw instrumentation.

SUMMARY OF BACKGROUND DATA

Treatment of single, structural, lumbar, and thoracolumbar curves in patients with AIS has been the subject of some debate. Advocates of the anterior approach assert that their technique spares posterior musculature and may save distal fusion levels, and that with dual rods and anterior column support the issues with nonunion and kyphosis have been obviated. Advocates of the posterior approach assert that with the change to posterior pedicle screw based instrumentation that correction and levels are equivalent, and the posterior approach avoids the issues with nonunion and kyphosis. This report directly compares the results of posterior versus anterior instrumented fusions in the operative treatment of adolescent idiopathic Lenke 5C curves.

METHODS

We analyzed 62 patients with Lenke 5C based on radiographic and clinical data at 2 institutions: 31 patients treated with posterior, pedicle-screw instrumented fusions at 1 institution (group PSF); and 31 patients with anterior, dual-rod instrumented fusions at another institution (group ASF). Multiple clinical and radiographic parameters were evaluated and compared.

RESULTS

The mean age, preoperative major curve magnitude, and preoperative lowest instrumented vertebral (LIV) tilt were similar in both groups (age: PSF = 15.5 years, ASF = 15.6 years; curve size: PSF = 50.3 degrees +/- 7.0 degrees , ASF = 49.0 degrees +/- 6.6 degrees ; LIV tilt: PSF = 27.5 degrees +/- 6.5 degrees , ASF = 27.8 degrees +/- 6.2 degrees ). After surgery, the major curve corrected to an average of 6.3 degrees +/- 3.2 degrees (87.6% +/- 5.8%) in the PSF group, compared with 12.1 degrees +/- 7.4 degrees (75.7% +/- 14.8%) in the ASF group (P < 0.01). At final follow-up, the major curve measured 8.0 degrees +/- 3.0 degrees (84.2% +/- 5.8% correction) in the PSF group, compared with 15.9 degrees +/- 9.0 degrees (66.6% +/- 17.9%) in the ASF group (P = 0.01). This represented a loss of correction of 1.7 degrees +/- 1.9 degrees (3.4% +/- 3.7%) in the PSF group, and 3.8 degrees +/- 4.2 degrees (9.4% +/- 10.7%) in the ASF group (P = 0.028). The LIV tilt decreased to 4.1 degrees +/- 3.4 degrees after surgery in the PSF group, and 4.5 degrees +/- 3.7 degrees in the ASF group. At final follow-up, the LIV tilt was 5.1 degrees +/- 3.5 degrees in the PSF group, and 4.5 degrees +/- 3.7 degrees in the ASF group. EBL was identical in both groups, and length of hospital stay was significantly (P < 0.01) shorter in the PSF group (4.8 vs. 6.1 days). There were no complications in either group which extended hospital stay or required an unplanned second surgery.

CONCLUSION

At a minimum of 2-year follow-up, adolescents with Lenke 5C curves demonstrated statistically significantly better curve correction, less loss of correction over time, and shorter hospital stays when treated with a posterior release with pedicle screw instrumented fusion compared with an anterior instrumented fusion with dual rods for similar patient populations.

摘要

研究设计

对 2 组接受 Lenke 5C 型青少年特发性脊柱侧凸(AIS)手术治疗的患者进行多中心分析。

目的

比较接受前路脊柱融合联合双棒内固定和前路柱支撑治疗的 Lenke 5C 脊柱侧凸患者与接受后路松解和椎弓根螺钉内固定治疗的患者。

背景资料概要

对于 AIS 患者的单节段、结构性、腰椎和胸腰椎侧凸的治疗一直存在争议。前路方法的支持者认为,他们的技术可以保留后路肌肉,并可能节省远端融合节段,而且使用双棒和前路柱支撑,非融合和后凸的问题已经得到解决。后路方法的支持者则认为,随着后路椎弓根螺钉内固定技术的改变,矫正和融合节段是等效的,而且后路方法避免了非融合和后凸的问题。本报告直接比较了后路与前路器械融合在青少年特发性 Lenke 5C 型脊柱侧凸的手术治疗中的结果。

方法

我们根据 2 个机构的影像学和临床数据分析了 62 例 Lenke 5C 患者:1 个机构的 31 例患者接受后路、椎弓根螺钉内固定融合治疗(PSF 组);另一个机构的 31 例患者接受前路、双棒内固定融合治疗(ASF 组)。对多个临床和影像学参数进行了评估和比较。

结果

两组患者的平均年龄、术前主要脊柱侧凸曲度和术前最低固定椎(LIV)倾斜度相似(年龄:PSF 组 15.5 岁,ASF 组 15.6 岁;曲度大小:PSF 组 50.3 度 +/- 7.0 度,ASF 组 49.0 度 +/- 6.6 度;LIV 倾斜度:PSF 组 27.5 度 +/- 6.5 度,ASF 组 27.8 度 +/- 6.2 度)。手术后,PSF 组主要脊柱侧凸矫正至平均 6.3 度 +/- 3.2 度(87.6% +/- 5.8%),而 ASF 组为 12.1 度 +/- 7.4 度(75.7% +/- 14.8%)(P < 0.01)。在最终随访时,PSF 组的主要脊柱侧凸测量值为 8.0 度 +/- 3.0 度(84.2% +/- 5.8%的矫正),而 ASF 组为 15.9 度 +/- 9.0 度(66.6% +/- 17.9%)(P = 0.01)。这代表 PSF 组的矫正丢失了 1.7 度 +/- 1.9 度(3.4% +/- 3.7%),ASF 组为 3.8 度 +/- 4.2 度(9.4% +/- 10.7%)(P = 0.028)。PSF 组术后 LIV 倾斜度降至 4.1 度 +/- 3.4 度,ASF 组为 4.5 度 +/- 3.7 度。在最终随访时,PSF 组的 LIV 倾斜度为 5.1 度 +/- 3.5 度,ASF 组为 4.5 度 +/- 3.7 度。两组的 EBL 相同,PSF 组的住院时间明显(P < 0.01)缩短(4.8 天 vs. 6.1 天)。两组均无因延长住院时间或需要计划外二次手术的并发症。

结论

在至少 2 年的随访中,Lenke 5C 型脊柱侧凸患者接受后路松解联合椎弓根螺钉内固定融合治疗的患者与接受前路器械融合联合双棒内固定治疗的患者相比,在曲度矫正、随时间推移的矫正丢失和住院时间方面均有统计学显著改善,且患者人群相似。

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