Reignier Jean, Dumont Romain, Katsahian Sandrine, Martin-Lefevre Laurent, Renard Benoit, Fiancette Maud, Lebert Christine, Clementi Eva, Bontemps Frederic
Medical-Surgical Intensive Care Unit, District Hospital Center, La Roche-sur-Yon, France.
Crit Care Med. 2008 Jul;36(7):2076-83. doi: 10.1097/CCM.0b013e31817c0ea7.
To assess decisions to forego life-sustaining treatment (LST) in patients too sick for intensive care unit (ICU) admission, comparatively to patients admitted to the ICU.
Prospective observational cohort study.
A medical-surgical ICU.
Consecutive patients referred to the ICU during a one-yr period.
None.
Of 898 triaged patients, 147 were deemed too well to benefit from ICU admission. Decisions to forego LST were made in 148 of 666 (22.2%) admitted patients and in all 85 patients deemed too sick for ICU admission. Independent predictors of decisions to forego LST at ICU refusal rather than after ICU admission were: age; underlying disease; living in an institution; preexisting cognitive impairment; admission for medical reasons; and acute cardiac failure, acute central neurologic illness, or sepsis. Hospital mortality after decisions to forego LST was not significantly different in refused and admitted patients (77.5% vs. 86.5%; p = .1). Decisions to forego LST were made via telephone in 58.8% of refused patients and none of the admitted patients. Nurses caring for the patient had no direct contact with the ICU physicians for 62.3% of the decisions in refused patients, whereas meetings between nurses and physicians occurred in 70.3% of decisions to forego LST in the ICU. Patients or relatives were involved in 28.2% of decisions to forego LST at ICU refusal compared with 78.4% of decisions to forego LST in ICU patients (p < .001).
All patients deemed too sick for ICU admission had decisions to forego LST. These decisions were made without direct patient examination in two-thirds of refused patients (vs. none of admitted patients) and were associated with less involvement of nurses and relatives compared with decisions in admitted patients. Further work is needed to improve decisions to forego LST made under the distinctive circumstances of triage.
评估对于因病情过重而无法入住重症监护病房(ICU)的患者,与入住ICU的患者相比,放弃生命维持治疗(LST)的决策情况。
前瞻性观察队列研究。
一所内科-外科ICU。
在一年期间转诊至ICU的连续患者。
无。
在898例经分诊的患者中,147例被认为病情过轻,无法从入住ICU中获益。666例入住患者中有148例(22.2%)做出了放弃LST的决策,而所有85例被认为病情过重无法入住ICU的患者均做出了该决策。在拒绝入住ICU而非入住后做出放弃LST决策的独立预测因素包括:年龄;基础疾病;居住在机构中;既往存在认知障碍;因医疗原因入院;以及急性心力衰竭、急性中枢神经系统疾病或脓毒症。放弃LST决策后的医院死亡率在拒绝入住和入住患者中无显著差异(77.5%对86.5%;p = 0.1)。58.8%的拒绝入住患者通过电话做出了放弃LST的决策,而入住患者中无人通过电话做出该决策。在拒绝入住患者中,62.3%的决策中护理患者的护士与ICU医生没有直接接触,而在ICU中放弃LST的决策中,70.3%的决策有护士与医生的会诊。与ICU患者放弃LST的决策相比,拒绝入住ICU时患者或亲属参与了28.2%的放弃LST决策(p < 0.001)。
所有被认为病情过重无法入住ICU的患者均做出了放弃LST的决策。在三分之二的拒绝入住患者中(与入住患者中无人情况相比),这些决策是在未直接对患者进行检查的情况下做出的,并且与入住患者的决策相比,护士和亲属的参与度较低。需要进一步开展工作以改进在分诊这一特殊情况下做出的放弃LST的决策。