Song Xiong, Liao Jia-Xuan
Department of Pediatrics, Maternal and Child Health Hospital/Children's Hospital, Guangxi Zhuang Autonomous Region, Nanning 530003, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2008 Jun;10(3):299-300.
To explore the value of electroencephalogram (EEG) in early diagnosis of brain injury in neonates with asphyxia.
EEG examination was performed in 49 neonates with asphyxia (mild: n=9; severe: n=40) within 6 hrs of their births. Of the 49 asphyxiated neonates, 33 had concurrent HIE, including 20 cases of mild, 9 cases of moderate and 4 cases of severe HIE.
Twenty-one (63.6%) out of the 33 patients with HIE showed abnormal EEG, but only one (6.3%) in the asphyxia group without HIE. All of 13 patients with moderate-severe HIE showed abnormal EEG. The degree of EEG abnormality in neonates with HIE was consistent with the clinical grading of HIE. The neonates whose EEG showed electrical silence and burst suppression and the abnormalities were kept unrecoverable for more than 2 weeks had very poor prognosis.
EEG can reflect brain injury caused by neonatal asphyxia and the severity of brain injury. It may be useful for early diagnosis of brain injury following asphyxia in neonates.
探讨脑电图（EEG）在新生儿窒息脑损伤早期诊断中的价值。
对49例窒息新生儿（轻度：n = 9；重度：n = 40）在出生后6小时内进行脑电图检查。49例窒息新生儿中，33例合并新生儿缺氧缺血性脑病（HIE），其中轻度20例，中度9例，重度4例。
33例HIE患儿中21例（63.6%）脑电图异常，而无HIE的窒息组仅1例（6.3%）异常。13例中重度HIE患儿脑电图均异常。HIE新生儿脑电图异常程度与HIE临床分度一致。脑电图呈电静息、爆发抑制且异常持续2周以上不能恢复者预后极差。
脑电图能反映新生儿窒息所致脑损伤及脑损伤严重程度，对新生儿窒息后脑损伤的早期诊断有一定价值。
