Li Bu-Yun, Yang Yi-Feng, Wu Zhong-Shi, Zhao Tian-Li, Yang Jin-Fu, Xiong Lian, Yin Ni, Xie Li
Department of Pediatric Cardiac Surgery, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2008 Jun;10(3):315-8.
This research reported the experience of early surgical treatment for infants with large atrial septal defects (ASD) or ventricular septal defects (VSD) complicated by pneumonia.
Between January 2003 and January 2008, 39 infants with large ASD or VSD complicated by pneumonia were admitted to the Second Xiangya Hospital. Thirty-six patients underwent surgical repair within 7-10 days after pneumonia had been controlled. Mean age was 5.4+/-3.4 months and mean weight was 4.7+/-1.6 kg in the 36 patients. Three patients received conservative treatment due to uncontrolled lung infections.
Of the 36 patients, 33 had successful surgery and 3 (8.3%) died of serious low cardiac output (n=1) or respiratory failure due to congenital tracheostenosis (n=2). The 33 survivors showed normal growth and development in a 6 month-5 year follow-up. Of the 3 patients receiving conservative treatment, 1 died of cardiopulmonary failure and 2 were discharged after the symptoms had been improved.
With increasing medical experience and technique, early surgical operation may be performed with good outcomes in infants with large ASD or VSD complicated by pneumonia.
本研究报告了对患有大型房间隔缺损（ASD）或室间隔缺损（VSD）并伴有肺炎的婴儿进行早期手术治疗的经验。
2003年1月至2008年1月期间，39例患有大型ASD或VSD并伴有肺炎的婴儿被收入中南大学湘雅二医院。36例患者在肺炎得到控制后的7 - 10天内接受了手术修复。这36例患者的平均年龄为5.4±3.4个月，平均体重为4.7±1.6千克。3例患者因肺部感染未得到控制而接受了保守治疗。
36例患者中，33例手术成功，3例（8.3%）死于严重的心输出量过低（1例）或因先天性气管狭窄导致的呼吸衰竭（2例）。33例幸存者在6个月至5年的随访中生长发育正常。3例接受保守治疗的患者中，1例死于心肺衰竭，2例症状改善后出院。
随着医疗经验和技术的不断提高，对于患有大型ASD或VSD并伴有肺炎的婴儿，早期手术治疗可能会取得良好的效果。
