Heikkilä Jukka, Taskinen Seppo, Toppari Jorma, Rintala Risto
Department of Pediatric Surgery, Hyvinkää Hospital, Hyvinkää, Finland.
J Urol. 2008 Aug;180(2):715-7. doi: 10.1016/j.juro.2008.04.043. Epub 2008 Jun 13.
We evaluated the incidence of cryptorchidism and inguinal hernias in patients with posterior urethral valves, and compared characteristics in patients with and without cryptorchidism or inguinal hernia.
A total of 200 patients with posterior urethral valves treated between 1953 and 2003 were identified from a hospital database. Patient records were retrospectively reviewed. The state of testicular descent and the presence of inguinal hernias were recorded in 192 patients. Patient characteristics were analyzed.
Of 192 patients 31 (16%) had cryptorchidism, which was bilateral in 9 (29%). A total of 21 patients (11%) had inguinal hernias that were not associated with cryptorchid testes. The patients with cryptorchidism, and to some extent the patients with hernias, appeared to have a more severe form of posterior urethral valves than those without cryptorchidism. At the time of diagnosis the median serum creatinine concentration was 100 mumol/l (range 38 to 460) in boys with cryptorchidism and 87 (14 to 593) in boys without cryptorchidism (p = 0.131). At 6-month followup the median serum creatinine levels were 90 mumol/l (range 31 to 573) in patients with cryptorchidism and 45 (19 to 504) in patients without cryptorchidism (p = 0.006). Cryptorchidism was also more common in cases diagnosed neonatally compared to those diagnosed at a later age (14 of 52 patients, 27% vs 14 of 112, 12.5%, respectively, p = 0.027).
The incidence of cryptorchidism and inguinal hernias requiring surgery is high in patients with posterior urethral valves. Patients with cryptorchidism appear to have a more severe form of posterior urethral valves than those with normal testes.
我们评估了后尿道瓣膜症患者中隐睾症和腹股沟疝的发生率，并比较了有或无隐睾症或腹股沟疝患者的特征。
从医院数据库中识别出1953年至2003年间接受治疗的200例后尿道瓣膜症患者。对患者记录进行回顾性审查。记录了192例患者的睾丸下降状态和腹股沟疝情况。对患者特征进行了分析。
192例患者中，31例（16%）患有隐睾症，其中9例（29%）为双侧隐睾。共有21例患者（11%）患有与隐睾无关的腹股沟疝。与无隐睾症的患者相比，隐睾症患者以及在一定程度上疝患者似乎患有更严重形式的后尿道瓣膜症。诊断时，隐睾症男孩的血清肌酐浓度中位数为100μmol/l（范围38至460），无隐睾症男孩为87（14至593）（p = 0.131）。在6个月随访时，隐睾症患者的血清肌酐水平中位数为90μmol/l（范围31至573），无隐睾症患者为45（19至504）（p = 0.006）。与晚些时候诊断的病例相比，隐睾症在新生儿期诊断的病例中也更常见（分别为52例中的14例，27% 对112例中的14例，12.5%，p = 0.027）。
后尿道瓣膜症患者中需要手术治疗的隐睾症和腹股沟疝的发生率较高。与睾丸正常的患者相比，隐睾症患者似乎患有更严重形式的后尿道瓣膜症。
