Storch Eric A, Milsom Vanessa A, Merlo Lisa J, Larson Michael, Geffken Gary R, Jacob Marni L, Murphy Tanya K, Goodman Wayne K
Department of Psychiatry, University of Florida, Gainesville, FL, USA.
Psychiatry Res. 2008 Aug 15;160(2):212-20. doi: 10.1016/j.psychres.2007.07.005. Epub 2008 Jun 16.
Insight has emerged as a significant treatment outcome predictor in adult obsessive-compulsive disorder (OCD), with some suggesting that OCD with poor insight represents a distinct clinical subtype. Despite its clinical relevance, limited data exist on insight in pediatric OCD patients. The present study investigated the relation between poor insight and clinical characteristics among children and adolescents with OCD (N=78, ages 6-20 years). Forty-five percent of the sample (n=35) was considered to have low levels of insight into their symptoms, as determined by clinician rating on item 11 of the Children's Yale-Brown Obsessive-Compulsive Scale. Pearson product-moment correlations showed a significant, inverse relation between insight and OCD severity. Relative to the high insight group, parents of patients with low insight reported higher levels of OCD-related impairment and family accommodation. These findings suggest that OCD with poor insight may represent a distinct clinical feature that may require more intensive and multimodal treatment approaches.
领悟已成为成人强迫症（OCD）重要的治疗结果预测指标，一些研究表明领悟力差的强迫症代表一种独特的临床亚型。尽管其具有临床相关性，但关于儿童强迫症患者领悟力的数据有限。本研究调查了强迫症儿童和青少年（N = 78，年龄6 - 20岁）领悟力差与临床特征之间的关系。根据临床医生对儿童耶鲁-布朗强迫症量表第11项的评分，45%的样本（n = 35）被认为对其症状的领悟水平较低。皮尔逊积差相关分析显示领悟力与强迫症严重程度之间存在显著的负相关。与高领悟力组相比，低领悟力患者的父母报告的强迫症相关损害和家庭迁就水平更高。这些发现表明领悟力差的强迫症可能代表一种独特的临床特征，可能需要更强化和多模式的治疗方法。
