University of British Columbia and BC Children's Hospital, Vancouver, BC, Canada.
Aarhus University Hospital, Denmark.
J Am Acad Child Adolesc Psychiatry. 2020 May;59(5):650-659.e2. doi: 10.1016/j.jaac.2019.05.030. Epub 2019 Jun 20.
Insight and avoidance are commonly discussed factors in obsessive-compulsive disorder (OCD) that have demonstrated associations with increased severity as well as reduced treatment response in adults, but these factors have not been sufficiently examined in pediatric OCD. This study examined the impacts of avoidance, insight, and impairment recognition concordance on cognitive-behavioral therapy (CBT) outcomes as well as impacts of CBT on insight and avoidance in a large sample of youths affected by OCD.
Data from 573 OCD-affected youths enrolled in CBT trials were aggregated. Children's Yale-Brown Obsessive-Compulsive Scale items measured treatment response, insight, and avoidance. Standardized differences between child and parent ratings of impairment were used to calculate impairment recognition concordance. Binary logistic regression was used to identify variables associated with treatment response.
Greater avoidance, limited child recognition of impairment, older age, and lower baseline severity predicted reduced likelihood of treatment response, but insight did not. Both insight and avoidance improved significantly following CBT. Response rates were lower when posttreatment insight and avoidance were worse.
Contrasting with prevailing belief, poor insight does not appear to limit CBT response potential in pediatric OCD. Avoidance and impairment recognition are understudied CBT response predictors and warrant further consideration in pediatric OCD. Clinicians should attend to these factors to optimize outcomes for children affected by this common, debilitating illness.
洞察和回避是强迫症(OCD)中经常讨论的因素,这些因素与成人中严重程度的增加以及治疗反应的降低有关,但在儿童 OCD 中尚未充分研究这些因素。本研究考察了回避、洞察和损伤识别一致性对认知行为疗法(CBT)结果的影响,以及 CBT 对大量受 OCD 影响的青少年的洞察和回避的影响。
汇总了 573 名参加 CBT 试验的 OCD 青少年的数据。儿童耶鲁-布朗强迫症量表的项目衡量了治疗反应、洞察和回避。使用儿童和父母对损伤的评分之间的标准化差异来计算损伤识别一致性。使用二项逻辑回归来确定与治疗反应相关的变量。
回避程度较高、儿童对损伤的认识有限、年龄较大和基线严重程度较低预测治疗反应的可能性降低,但洞察力没有。洞察和回避在 CBT 后都显著改善。当治疗后洞察和回避更差时,反应率更低。
与普遍观点相反,在儿童 OCD 中,洞察力差似乎不会限制 CBT 的反应潜力。回避和损伤识别是研究较少的 CBT 反应预测因素,值得在儿童 OCD 中进一步考虑。临床医生应关注这些因素,以优化受这种常见、使人衰弱的疾病影响的儿童的治疗效果。