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家庭医学中疑难诊断问题的诊断准确性及安全管理的预测因素

Predictors of diagnostic accuracy and safe management in difficult diagnostic problems in family medicine.

作者信息

Kostopoulou Olga, Oudhoff Jurriaan, Nath Radhika, Delaney Brendan C, Munro Craig W, Harries Clare, Holder Roger

机构信息

Primary Care Clinical Sciences, University of Birmingham, Birmingham, UK.

出版信息

Med Decis Making. 2008 Sep-Oct;28(5):668-80. doi: 10.1177/0272989X08319958. Epub 2008 Jun 12.

Abstract

OBJECTIVE

To investigate the role of information gathering and clinical experience on the diagnosis and management of difficult diagnostic problems in family medicine.

METHOD

Seven diagnostic scenarios including 1 to 4 predetermined features of difficulty were constructed and presented on a computer to 84 physicians: 21 residents in family medicine, 21 family physicians with 1 to 3 y in practice, and 42 family physicians with >or=10 y in practice. Following the Active Information Search process tracing approach, participants were initially presented with a patient description and presenting complaint and were subsequently able to request further information to diagnose and manage the patient. Evidence-based scoring criteria for information gathering, diagnosis, and management were derived from the literature and a separate study of expert opinion.

RESULTS

Rates of misdiagnosis were in accordance with the number of features of difficulty. Seventy-eight percent of incorrect diagnoses were followed by inappropriate management and 92% of correct diagnoses by appropriate management. Number of critical cues requested (cues diagnostic of any relevant differential diagnoses in a scenario) was a significant predictor of accuracy in 6 scenarios: 1 additional critical cue increased the odds of obtaining the correct diagnosis by between 1.3 (95% confidence interval [CI], 1.0-1.8) and 7.5 (95% CI, 3.2- 17.7), depending on the scenario. No effect of experience was detected on either diagnostic accuracy or management. Residents requested significantly more cues than experienced family physicians did.

CONCLUSIONS

Supporting the gathering of critical information has the potential to improve the diagnosis and management of difficult problems in family medicine.

摘要

目的

探讨信息收集和临床经验在家庭医学疑难诊断问题的诊断与管理中的作用。

方法

构建了七个包含1至4个预定困难特征的诊断场景,并通过计算机呈现给84名医生:21名家庭医学住院医师、21名从业1至3年的家庭医生以及42名从业≥10年的家庭医生。按照主动信息搜索过程追踪方法,最初向参与者呈现患者描述和就诊主诉,随后他们能够请求进一步信息以对患者进行诊断和管理。信息收集、诊断和管理的循证评分标准源自文献以及一项单独的专家意见研究。

结果

误诊率与困难特征的数量相符。78%的错误诊断之后是不恰当的管理,92%的正确诊断之后是恰当的管理。所请求的关键线索数量(场景中对任何相关鉴别诊断具有诊断意义的线索)在6个场景中是准确性的显著预测指标:每增加1条关键线索,获得正确诊断的几率增加1.3(95%置信区间[CI],1.0 - 1.8)至7.5(95%CI,3.2 - 17.7),具体取决于场景。未检测到经验对诊断准确性或管理有任何影响。住院医师请求的线索显著多于经验丰富的家庭医生。

结论

支持关键信息的收集有可能改善家庭医学中疑难问题的诊断与管理。

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