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[脑炎与体液免疫]

[Encephalitis and humoral immunity].

作者信息

Weippl G, Harasek H, Unger F, Eigl M, Sitko C, Kucera H

出版信息

Padiatr Padol. 1976;11(4):592-9.

PMID:185568
Abstract

Fourteen children with viral infection of the central nervous system have been examined with respect to their function of humoral immunity. Serum concentrations of immune globulins have been measured and antibody titers determined. Iso- and hetero agglutinins as well as antibodies against diphtheria, pertussis, and tetanus if the children were vaccinated have been measured. Anti viral antibodies were tested if children reported the respective infection in their history. Selective antibody deficiency have been found in three children all of whom had normal serum IgG and two elevated IgM levels. These three children showed complications in the course of infection. Nine children had elevated serum IgM and titers of IgM-antibodies were also in or above the high normal range.

摘要

对14名患有中枢神经系统病毒感染的儿童进行了体液免疫功能检查。测量了免疫球蛋白的血清浓度并测定了抗体滴度。检测了同种和异种凝集素,以及如果儿童接种过疫苗,还检测了针对白喉、百日咳和破伤风的抗体。如果儿童有相关感染史,则检测抗病毒抗体。在3名儿童中发现了选择性抗体缺乏,他们的血清IgG均正常,2名儿童的IgM水平升高。这3名儿童在感染过程中出现了并发症。9名儿童的血清IgM升高,IgM抗体滴度也在高正常范围或高于高正常范围。

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