印度西孟加拉邦马尔达地区三个人口中血红蛋白E的高流行率。
High prevalence of haemoglobin E in three populations of the Malda district, West Bengal, India.
作者信息
Das M K, Dey B, Roy M, Mukherjee B N
机构信息
Anthropometry and Human Genetics Unit, Indian Statistical Institute, Calcutta.
出版信息
Hum Hered. 1991;41(2):84-8. doi: 10.1159/000153983.
PMID:1855786
Abstract
High frequencies of haemoglobin (Hb) E were reported earlier from Assam in northeast India. In the present study one of the three populations of the Malda district of West Bengal, called the Deshi, was found to show one of the highest incidences of the Hb E gene (0.61) recorded so far. A founder effect and/or local inbreeding may possibly explain this observation.
摘要
印度东北部阿萨姆邦早前曾报道过高频率的血红蛋白E（Hb E）。在本研究中，西孟加拉邦马尔达区的三个群体之一，即德希群体，被发现呈现出迄今为止所记录的Hb E基因的最高发病率之一（0.61）。奠基者效应和/或本地近亲繁殖可能可以解释这一观察结果。
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