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维多利亚州墨尔本与γ-羟基丁酸(GHB)相关的救护车出勤模式及发生率

Patterns and incidence of gamma-hydroxybutyrate (GHB)-related ambulance attendances in Melbourne, Victoria.

作者信息

Dietze Paul M, Cvetkovski Stefan, Barratt Monica J, Clemens Susan

机构信息

Centre for Epidemiology and Population Health Research, Burnet Institute, Melbourne, VIC.

出版信息

Med J Aust. 2008 Jun 16;188(12):709-11. doi: 10.5694/j.1326-5377.2008.tb01851.x.

Abstract

OBJECTIVE

To examine the nature and extent of ambulance attendances involving gamma-hydroxybutyrate (GHB) and to compare these with heroin-related attendances in Melbourne, Victoria.

DESIGN

Retrospective analysis of a database of ambulance service records on attendances at non-fatal drug overdoses, March 2001-October 2005.

PARTICIPANTS AND SETTING

Patients who took GHB and were attended to by an ambulance, as recorded by Metropolitan Ambulance Service (Melbourne) paramedics.

MAIN OUTCOME MEASURES

Transportation to hospital by ambulance; other outcomes included number, age, sex and Glasgow Coma Score (GCS) of patients, characteristics of attendances (in public or private space, others present, police co-attendance).

RESULTS

There were 618 GHB-related ambulance attendances across the 46 months of data collection; 362 involving GHB only and 256 involving the concurrent use of GHB and other drugs. These figures compare to 3723 heroin overdoses observed during the same period. The number of GHB-related attendances increased by around 4% per month, which was a higher rate of increase than that found for heroin overdose attendances. Most patients were younger than 25 years, were attended in public spaces, and had a GCS <10. Around 90% of patients were transported to hospital, compared with 21% of heroin overdose attendances.

CONCLUSIONS

Ambulance attendance data can be used to index GHB-associated harms. The clear increases in GHB-related ambulance attendances over time highlights the need for further research on how best to respond to this emergent drug-related harm.

摘要

目的

研究涉及γ-羟基丁酸(GHB)的救护车出诊的性质和范围,并将其与维多利亚州墨尔本地区与海洛因相关的出诊情况进行比较。

设计

对2001年3月至2005年10月期间非致命药物过量出诊的救护车服务记录数据库进行回顾性分析。

参与者及地点

由墨尔本都市救护车服务中心护理人员记录的服用GHB且由救护车出诊的患者。

主要观察指标

通过救护车送往医院;其他结果包括患者的数量、年龄、性别和格拉斯哥昏迷评分(GCS),出诊特征(在公共或私人场所、有无他人在场、警察协同出诊)。

结果

在46个月的数据收集期间,共有618次与GHB相关的救护车出诊;362次仅涉及GHB,256次涉及GHB与其他药物同时使用。同期观察到3723次海洛因过量服用情况。与GHB相关的出诊次数每月增加约4%,这一增长率高于海洛因过量服用出诊次数的增长率。大多数患者年龄小于25岁,在公共场所接受救治,格拉斯哥昏迷评分<10分。约90%的患者被送往医院,而海洛因过量服用出诊患者中这一比例为21%。

结论

救护车出诊数据可用于衡量与GHB相关的危害。随着时间推移,与GHB相关的救护车出诊次数明显增加,这凸显了有必要进一步研究如何最好地应对这种新出现的与药物相关的危害。

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