Aubert P, Lainée J, Duron F
Nouv Presse Med. 1976 Oct 16;5(34):2227-30.
Isolated adrenocorticotropin deficiencies are rare. Two cases are reported, one, with hypoglycaemia, the other with weakness and hypotension, with a review of the published cases during the past twenty years. The adrenal defect impairs severely the glucocorticoid secretion while aldosteron is normal. Tetracosactid stimulates adrenal secretion. ACTH activity measurable in serum is very low and not affected by metyrapone. Other pituitary secretions are normal. The hypothalamic or pituitary level of the defect will be situated when CRH test available.
孤立性促肾上腺皮质激素缺乏症较为罕见。本文报告了两例病例，一例伴有低血糖，另一例伴有虚弱和低血压，并对过去二十年中已发表的病例进行了综述。肾上腺缺陷严重损害糖皮质激素分泌，而醛固酮分泌正常。二十四肽促皮质素能刺激肾上腺分泌。血清中可测得的促肾上腺皮质激素活性非常低，且不受甲吡酮影响。其他垂体分泌功能正常。当有促肾上腺皮质激素释放激素（CRH）试验时，将确定缺陷位于下丘脑或垂体水平。
