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无均整器直线加速器产生的中子的能谱、来源及屏蔽考量

Energy spectra, sources, and shielding considerations for neutrons generated by a flattening filter-free Clinac.

作者信息

Kry Stephen F, Howell Rebecca M, Titt Uwe, Salehpour Mohammad, Mohan Radhe, Vassiliev Oleg N

机构信息

Department of Radiation Physics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

出版信息

Med Phys. 2008 May;35(5):1906-11. doi: 10.1118/1.2905029.

Abstract

Neutron production is an unwanted result of high-energy radiation therapy and results in secondary exposure of patients and radiation therapists to radiation. Recent studies have shown that delivering therapy using a standard medical accelerator with the flattening filter removed may reduce neutron fluence by nearly 70% over the course of prostate intensity-modulated radiation therapy (IMRT). In the current study, the 197Au Bonner sphere technique was used to compare the neutron spectrum produced when the filter is present and when it is absent. In addition, the following was calculated: (1) the neutron-shielding parameters of source strength and ambient dose equivalent (H0) and (2) using the Monte Carlo technique, the sources of neutron production in the accelerator head. It was found that the neutron spectrum was nearly constant, regardless of the presence of the flattening filter; however, the total fluence and ambient dose equivalent over the course of prostate IMRT were more than 70% lower when the filter was removed. Similarly, shielding parameters were lower when the filter was removed. Finally, the primary collimator and jaws accounted for the majority of neutron production, both with and without the flattening filter; however, with the flattening filter removed, the upper jaw accounted for much more neutron production relative to when the filter was present. Ultimately, removal of the flattening filter may offer several clinical advantages, including a reduction in the dose from neutrons to the patient and to radiation personnel.

摘要

中子产生是高能放射治疗产生的不良结果,会导致患者和放射治疗师受到二次辐射。最近的研究表明,在前列腺调强放射治疗(IMRT)过程中,使用移除了均整滤过器的标准医用加速器进行治疗,可使中子注量降低近70%。在本研究中,采用¹⁹⁷Au邦纳球技术比较了有均整滤过器和无均整滤过器时产生的中子能谱。此外,还进行了以下计算:(1)源强和周围剂量当量(H₀)的中子屏蔽参数,以及(2)使用蒙特卡罗技术计算加速器头部中子产生的来源。结果发现,无论是否存在均整滤过器,中子能谱几乎是恒定的;然而,在前列腺IMRT过程中,移除滤过器时的总注量和周围剂量当量降低了70%以上。同样,移除滤过器时屏蔽参数也较低。最后,无论是有均整滤过器还是无均整滤过器,初级准直器和准直器钳口都是中子产生的主要来源;然而,移除均整滤过器后,相对于有滤过器时,上准直器钳口产生的中子要多得多。最终,移除均整滤过器可能会带来一些临床优势,包括减少患者和放射工作人员所接受的中子剂量。

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