系统性红斑狼疮患者胸腺中的黏膜相关淋巴组织淋巴瘤

Mucosa-associated lymphoid tissue lymphoma in the thymus of a patient with systemic lupus erythematosus.

作者信息

Maeda Ai, Hayama Makio, Nakata Masao, Masaki Hisao, Tanemoto Kazuo

机构信息

Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Kawasaki Medical School, 577 Matsushima Kurashiki, Okayama 701-0192, Japan.

出版信息

Gen Thorac Cardiovasc Surg. 2008 Jun;56(6):288-91. doi: 10.1007/s11748-008-0237-8. Epub 2008 Jun 18.

DOI:10.1007/s11748-008-0237-8

PMID:18563524

Abstract

Mucosa-associated lymphoid tissue (MALT) lymphoma arising from the thymus is extremely rare. We present a case of a 23-year-old woman with systemic lupus erythematosus (SLE) who was diagnosed with thymic MALT lymphoma. In 2004, she was diagnosed with a mediastinal tumor on chest radiography during medical follow up for SLE. An anterior mediastinal tumor with multilobular cysts was identified by computerized tomography and magnetic resonance imaging. A thymic malignancy was suspected and an extended thymectomy was performed. After histological and immunohistochemical examinations, the thymic tumor was diagnosed as a MALT lymphoma. There was no recurrence in the 2-year follow-up during which time there was no further treatment.

摘要

起源于胸腺的黏膜相关淋巴组织（MALT）淋巴瘤极为罕见。我们报告一例23岁患有系统性红斑狼疮（SLE）的女性患者，她被诊断为胸腺MALT淋巴瘤。2004年，她在SLE的医学随访期间胸部X线检查发现纵隔肿瘤。计算机断层扫描和磁共振成像显示前纵隔有一个多小叶囊肿的肿瘤。怀疑为胸腺恶性肿瘤并进行了扩大胸腺切除术。经过组织学和免疫组化检查，胸腺肿瘤被诊断为MALT淋巴瘤。在2年的随访期间没有复发，在此期间未进行进一步治疗。