Katsuda Yoshio, Leemingsawat Somjai, Thongrungkiat Supatra, Prummonkol Samreng, Samung Yudthana, Kanzaki Tsutomu, Watanabe Tomoe, Kahara Tomoko
Research and Development Laboratory, Dainihon Jochugiku, Osaka, Japan.
Southeast Asian J Trop Med Public Health. 2008 Mar;39(2):229-34.
Four strains (SS, BS, A and B) of Aedes aegypti collected from different sites in Bangkok and at different times were examined for their pyrethroid susceptibility. Mosquito coils containing dl, d-T80-allethrin, d, d-T-prallethrin and methoxymethyl-tetrafluorobenzyl tetramethyl-cyclopropanecarboxylate (K-3050) with or without a synergist were tested by the 25 m3 semi-field test method. One strain (SS) was the most susceptible with KT50 values of about < 30 minutes for all mosquito coils, while the other three strains (BS, A and B) were found to be around 10 to 20 times more tolerant to pyrethroids than the SS strain. A similar tendency for the pyrethroid susceptibility of the four strains was obtained with tests by topical application method. In field efficacy tests, mosquito coils with d, d-T-prallethrin 0.20% plus N-(2-ethylhexyl)bicycle-[2,2,1]- hept-5- ene-2,3-dicarboxyimide as a synergist exhibited a repellent effect of about 85%, while those with K-3050 0.10% plus the synergist exhibited a greater repellent effect of about 90%. In contrast, the repellent effect of commercial dl, d-T80-allethrin 0.20% coils was as low as about 50%. The d, d-T-prallethrin and K-3050 coils with the synergist were confirmed to be highly effective in repelling Ae. aegypti.
对从曼谷不同地点和不同时间采集的四株埃及伊蚊（SS、BS、A和B）进行了拟除虫菊酯敏感性检测。采用25立方米半野外试验方法，对含有右旋反式烯丙菊酯、右旋炔丙菊酯和甲氧甲基四氟苄基四甲基环丙烷羧酸酯（K - 3050）且添加或未添加增效剂的蚊香进行了测试。其中一株（SS）对所有蚊香的KT50值约<30分钟，最为敏感，而其他三株（BS、A和B）对拟除虫菊酯的耐受性比SS株高约10至20倍。通过点滴法测试，这四株埃及伊蚊对拟除虫菊酯的敏感性也呈现出类似趋势。在现场药效试验中，含0.20%右旋炔丙菊酯加N -（2 - 乙基己基）双环-[2,2,1]-庚 - 5 - 烯 - 2,3 - 二羧酸亚胺作为增效剂的蚊香驱蚊效果约为85%，而含0.10% K - 3050加增效剂的蚊香驱蚊效果更佳，约为90%。相比之下，市售含0.20%右旋反式烯丙菊酯蚊香的驱蚊效果低至约50%。含增效剂的右旋炔丙菊酯和K - 3050蚊香被证实对埃及伊蚊具有高效驱蚊作用。
