Impact of preoperative CA 15-3 levels in operable breast cancer. Comparison with tissue polypeptide antigen (TPA) and carcinoembryonic antigen (CEA).

作者信息

Iaffaioli R V, Caponigro F, Esposito G, Pagliarulo C, Deplacido S, Ungaro B, Bazzicalupo L, Frasci G, Bianco A R

机构信息

Division of Medical Oncology, University of Cagliari, Italy.

出版信息

Int J Biol Markers. 1991 Jan-Mar;6(1):21-4. doi: 10.1177/172460089100600104.

CA 15-3, TPA and CEA were assayed before surgery in 60 patients with breast cancer. A significant association was found between preoperative CA 15-3 levels and some of the most important prognostic factors in breast cancer, such as lymph node status and tumor size. No similar association was discovered for CEA and TPA. Preoperative CA 15-3 levels were also significantly associated with early recurrences of the disease, thus adding useful information to prognosis especially in N+ patients.