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[中毒性昏迷后伴有严重低温的心脏骤停三小时后的复苏]

[Resuscitation after three hours of cardiac arrest with severe hypothermia following a toxic coma].

作者信息

Gillart T, Loiseau S, Azarnoush K, Gonzalez D, Guelon D

机构信息

Département d'anesthésie-réanimation, hôpital Gabriel-Montpied, CHU de Clermont-Ferrand, B.P. 69, 63003 Clermont-Ferrand, France.

出版信息

Ann Fr Anesth Reanim. 2008 Jun;27(6):510-3. doi: 10.1016/j.annfar.2008.04.018. Epub 2008 Jun 18.

Abstract

We report the case of a 37-year-old woman who survived from severe hypothermia (rectal temperature: 22 degrees C) and prolonged cardiac arrest with asystole after benzodiazepine and tricyclic antidepressant poisoning. Basic-cardiopulmonary resuscitation and mechanical ventilation was started by a French Mobile Intensive-Care unit. Spontaneous circulation was restored at 25 degrees C under epinephrin after three hours of chest compression from home to the intensive-care unit and rewarming with extracorporeal circulation. The patient was discharged at day 13 without any neurological deficit. The discussion focuses on the benefit of extracorporeal-membrane oxygenation (ECMO) as extracorporeal circulation device through femoral access, the differential diagnosis between death and recoverable cardiac arrest and neuroprotection.

摘要

我们报告了一例37岁女性的病例,该患者在苯二氮䓬类药物和三环类抗抑郁药中毒后,从严重低温(直肠温度:22摄氏度)及伴有心搏停止的长时间心脏骤停中存活下来。法国移动重症监护小组启动了基础心肺复苏和机械通气。在从家中转运至重症监护病房并通过体外循环复温的过程中,经三小时胸外按压后,患者在25摄氏度时使用肾上腺素恢复了自主循环。患者于第13天出院,无任何神经功能缺损。讨论集中在作为经股动脉通路体外循环装置的体外膜肺氧合(ECMO)的益处、死亡与可恢复性心脏骤停的鉴别诊断以及神经保护方面。

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