Eftekhari Nahid, Mirzaei Fatemeh, Karimi Mehdi
Obstetrics & Gynecology Department, Afzalipour Hospital, Kerman, Iran.
Gynecol Endocrinol. 2008 May;24(5):289-91. doi: 10.1080/09513590701672355.
Abnormal uterine bleeding is one of the most common gynecological problems in women aged 15-45 years. The relationship of hyperprolactinemia with reproductive disorders, amenorrhea and irregular menstrual cycles has been known. The aim of the present study was to determine the frequency of hyperprolactinemia and galactorrhea in 15-45-year-old females with abnormal uterine bleeding.
This analytic descriptive study was carried out on 100 women referred to a gynecology clinic for vaginal bleeding without any organic disorder. Consecutive sampling was performed.
Among the cases 61% had hyperprolactinemia and galactorrhea was reported in 48% of these patients. There was a significant association between hyperprolactinemia and galactorrhea (p = 0.003); 46% of patients with galactorrhea and 75% of patients without galactorrhea had a high level of prolactin. Galactorrhea and hyperprolactinemia had no significant association with the type of abnormal uterine bleeding. Among patients with undiagnosed vaginal bleeding, hyperprolactinemia was present in more than 50% of them and in 46% it was associated with galactorrhea.
Hyperprolactinemia that presents a gynecological problem may or may not be accompanied by galactorrhea, and galactorrhea cannot be a certain index for hyperprolactinemia.
异常子宫出血是15 - 45岁女性中最常见的妇科问题之一。高催乳素血症与生殖紊乱、闭经和月经周期不规律之间的关系已为人所知。本研究的目的是确定15 - 45岁异常子宫出血女性中高催乳素血症和溢乳的发生率。
本分析性描述性研究对100名因阴道出血而转诊至妇科门诊且无任何器质性疾病的女性进行。采用连续抽样。
在这些病例中，61%患有高催乳素血症，其中48%的患者有溢乳现象。高催乳素血症与溢乳之间存在显著关联（p = 0.003）；有溢乳的患者中46%以及无溢乳的患者中75%催乳素水平较高。溢乳和高催乳素血症与异常子宫出血的类型无显著关联。在未确诊阴道出血的患者中，超过50%存在高催乳素血症，其中46%伴有溢乳。
呈现妇科问题的高催乳素血症可能伴有或不伴有溢乳，溢乳不能作为高催乳素血症的确定指标。
