Saharinen Tarja, Hintikka Jukka, Niskanen Leo, Kylmä Jari, Honkalampi Kirsi, Nikkonen Merja, Haatainen Kaisa, Koivumaa-Honkanen Heli, Viinamäki Heimo
Department of Psychiatry, Kuopio University Hospital, Kuopio, Finland.
Nord J Psychiatry. 2008;62(2):106-12. doi: 10.1080/08039480801962921.
It is not known whether somatic factors related to overall health and lifestyles or psychological factors, including confirmed psychiatric diagnoses, are associated with the health-related quality of life (HRQL) of men in a population-based sample. The aim of this study was to investigate socio-demographic, somatic and psychological factors associated with HRQL in men having mental symptoms during the 7 previous years. This cross-sectional sample of men (n=63) was investigated in 2004-05 and was based on a previous three-phase follow-up study that began in 1998. Blood pressure, body mass index, waist circumference, serum lipids and testosterone levels were measured. Psychiatric diagnoses were confirmed with using the Structured Clinical Interview for DSM-IV. Several mental symptoms were assessed with standardized scales. HRQL was measured with the RAND-36 using the physical (PCS) and mental component summary (MCS) scores. A poor HRQL in PCS was found in 73% of men and in MCS in 54%. Depressive symptoms, life dissatisfaction, male symptoms of aging and alexithymia were associated with both impaired PCS and MCS scores. Hopelessness, lifetime and current diagnoses of major depressive disorder and signs of suicidality only associated with a poorer MCS score. Somatic factors describing lifestyles and overall health only weakly associated with HRQL. In general, HRQL was poor in men having long-term mental symptoms. Mental health factors were strongly associated with PCS and MCS scores of HRQL. In improving HRQL in men, both physical and mental domains should be targeted in preventive and curative strategies.
在一个基于人群的样本中，与整体健康和生活方式相关的躯体因素或心理因素（包括已确诊的精神疾病诊断）是否与男性的健康相关生活质量（HRQL）相关尚不清楚。本研究的目的是调查在过去7年中有精神症状的男性中，与HRQL相关的社会人口学、躯体和心理因素。该横断面样本中的男性（n = 63）于2004 - 2005年进行了调查，其基于一项始于1998年的先前的三阶段随访研究。测量了血压、体重指数、腰围、血脂和睾酮水平。使用DSM - IV的结构化临床访谈确认精神疾病诊断。用标准化量表评估了几种精神症状。使用RAND - 36通过身体（PCS）和精神成分总结（MCS）得分来测量HRQL。73%的男性PCS得分低，54%的男性MCS得分低。抑郁症状、生活不满意、男性衰老症状和述情障碍与PCS和MCS得分受损均相关。绝望感、重度抑郁症的终生和当前诊断以及自杀迹象仅与较差的MCS得分相关。描述生活方式和整体健康的躯体因素与HRQL仅存在微弱关联。总体而言，有长期精神症状的男性HRQL较差。心理健康因素与HRQL的PCS和MCS得分密切相关。在改善男性的HRQL方面，预防和治疗策略应同时针对身体和精神领域。
